Makatsariia A D, Mishchenko A L, Kazakova L A, Kiriushchenkov P A
Akush Ginekol (Mosk). 1989 Aug(8):30-3.
In the presence of low-dosage administrations of heparin the system of hemostasis was studied in 50 pregnant females with placental failure and the chronic DIC syndrome. The efficacy of the treatment conducted was assessed with regard to the revealed levels of coagulation natural inhibitors, the products of fibrinogen-fibrin degradation, the degree of thrombocytic functional recovery and stabilization of the chronometric values of coagulation. The latter parameters considered together with the levels of heparinemia served as the criteria for the safety of the drug dosages employed.
在50例患有胎盘功能不全和慢性弥散性血管内凝血综合征的孕妇中,研究了低剂量肝素给药情况下的止血系统。根据所揭示的凝血天然抑制剂水平、纤维蛋白原 - 纤维蛋白降解产物、血小板功能恢复程度以及凝血计时值的稳定性,评估了所进行治疗的疗效。将后述参数与肝素血症水平一并考虑,作为所用药物剂量安全性的标准。