Novikova R I, Chernyĭ V I, Kaba'nko T P, Kuznetsova I V, Rudneva A A
Akush Ginekol (Mosk). 1989 Aug(8):49-51.
Therapeutic management of 42 parturients with the syndrome of obstetric coagulopathy who had suffered hemorrhagic shock in labor or early postpartum period was analysed. The signs of consumption coagulopathy were revealed in all the examinees. A decrease in the blood fibrinolytic activity observed in the presence of hypocirculation led to a microcirculatory crisis and the development of polyorganic failure. Agents of fibrinolytic activation and disaggregation from the nicotinic acid group or its derivatives, which were given in the postresuscitation period potentiated the therapeutic efficacy and therefore decreased lethality rates.
分析了42例在分娩期或产后早期发生出血性休克的产科凝血病综合征产妇的治疗处理情况。所有受检者均出现消耗性凝血病的体征。在存在微循环障碍的情况下观察到血液纤溶活性降低,导致微循环危机和多器官功能衰竭的发生。在复苏后期给予烟碱酸组或其衍生物的纤溶激活和解聚剂可增强治疗效果,从而降低死亡率。