Mudri Martina, Coriolano Kamary, Bütter Andreana
Division of General Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
J Pediatr Surg. 2017 May;52(5):791-794. doi: 10.1016/j.jpedsurg.2017.01.050. Epub 2017 Jan 30.
The purpose of this study was to determine if nonoperative management of acute appendicitis in children is more cost effective than appendectomy.
A retrospective review of children (6-17years) with acute appendicitis treated nonoperatively (NOM) from May 2012 to May 2015 was compared to similar patients treated with laparoscopic appendectomy (OM) (IRB#107535). Inclusion criteria included symptoms ≤48h, localized peritonitis, and ultrasound confirmation of acute appendicitis. Variables analyzed included failure rates, complications, length of stay (LOS), and cost analysis.
26 NOM patients (30% female, mean age 12) and 26 OM patients (73% female, mean age 11) had similar median initial LOS (24.5h (NOM) vs 16.5h (OM), p=0.076). Median total LOS was significantly longer in the NOM group (34.5h (NOM) vs 17.5 (OM), p=0.01). Median cost of appendectomy was $1416.14 (range $781.24-$2729.97). 9/26 (35%) NOM patients underwent appendectomy for recurrent appendicitis. 4/26 (15%) OM patients were readmitted (postoperative abscess (n=2), Clostridium difficile colitis (n=1), postoperative nausea/vomiting (n=1)). Median initial hospital admission costs were significantly higher in the OM group ($3502.70 (OM) vs $1870.37 (NOM), p=0.004)). However, median total hospital costs were similar for both groups ($3708.68 (OM) vs $2698.99 (NOM), p=0.065)).
Although initial costs were significantly less in children with acute appendicitis managed nonoperatively, total costs were similar for both groups. The high failure rate of nonoperative management in this series contributed to the total increased cost in the NOM group.
3b.
本研究旨在确定儿童急性阑尾炎的非手术治疗是否比阑尾切除术更具成本效益。
对2012年5月至2015年5月接受非手术治疗(NOM)的6至17岁急性阑尾炎患儿进行回顾性研究,并与接受腹腔镜阑尾切除术(OM)的类似患者进行比较(IRB#107535)。纳入标准包括症状持续时间≤48小时、局限性腹膜炎以及超声确诊为急性阑尾炎。分析的变量包括失败率、并发症、住院时间(LOS)和成本分析。
26例接受非手术治疗的患者(30%为女性,平均年龄12岁)和26例接受手术治疗的患者(73%为女性,平均年龄11岁)的初始住院时间中位数相似(24.5小时(非手术治疗组)对16.5小时(手术治疗组),p = 0.076)。非手术治疗组的总住院时间中位数显著更长(34.5小时(非手术治疗组)对17.5小时(手术治疗组),p = 0.01)。阑尾切除术的中位数成本为1416.14美元(范围为781.24美元至2729.97美元)。9/26(35%)的非手术治疗患者因复发性阑尾炎接受了阑尾切除术。4/26(15%)的手术治疗患者再次入院(术后脓肿(n = 2)、艰难梭菌结肠炎(n = 1)、术后恶心/呕吐(n = 1))。手术治疗组的初始住院费用中位数显著更高(3502.70美元(手术治疗组)对1870.37美元(非手术治疗组),p = 0.004)。然而,两组的总住院费用中位数相似(3708.6美元(手术治疗组)对2698.99美元(非手术治疗组),p = 0.065)。
虽然急性阑尾炎患儿非手术治疗的初始成本显著较低,但两组的总成本相似。本系列中非手术治疗的高失败率导致了非手术治疗组的总成本增加。
3b。