Nakanishi Kyoko, Sugiyama Kumi, Abe Yasushi, Endo Tetsushi, Ohsaki Yoshinobu
Dept. of Palliative Care, Asahikawa Medical University Hospital [Currently Dept. of Palliative Care, Asahikawa-Kosei General Hospital].
Gan To Kagaku Ryoho. 2017 Jan;44(1):63-65.
A 62-year-old male was diagnosed with large cell lung cancer(c-Stage IV)based on pathological examination of an anterior chest tumor. He received chemotherapy with cisplatin, pemetrexed, and bevacizumab. He suffered from persistent hiccups from day 2 of the first course of chemotherapy. He was unsuccessfully treated with chlorpromazine, shakuyakukanzoto, and gabapentin. Therefore, we administered pregabalin to him, and his hiccups subsided immediately. To prevent hiccups, he subsequently took pregabalin along with his chemotherapy regimen, and was able to receive 4 courses of chemotherapy without persistent hiccups. Pregabalin is a possible therapeutic option for treating persistent chemotherapy-induced hiccups.
一名62岁男性经前胸肿瘤病理检查确诊为大细胞肺癌（临床分期IV期）。他接受了顺铂、培美曲塞和贝伐单抗化疗。自化疗第一疗程第2天起，他持续呃逆。使用氯丙嗪、芍药甘草汤和加巴喷丁治疗均无效。因此，我们给他使用了普瑞巴林，呃逆随即缓解。为预防呃逆，他随后在化疗期间服用普瑞巴林，得以顺利完成4个疗程化疗，未再出现持续性呃逆。普瑞巴林可能是治疗持续性化疗引起呃逆的一种有效选择。
