Walsh A W, Magargal L E, Wright F, Donoso L A
Retina Vascular Unit, Wills Eye Hospital, Thomas Jefferson University Philadelphia, PA 19107.
Ann Ophthalmol. 1989 Sep;21(9):348-50.
During the course of age-related macular degeneration, the visual prognosis is abruptly changed when the presence of a subretinal neovascular membrane (SRNVM) is established by intravenous fluorescein angiography (IVFA). Patients who have been alerted to this condition may notice distortion on the Amsler grid and report within days of the onset of symptoms. Unfortunately most patients either do not notice the early changes in central vision or incorrectly attribute these symptoms to the development of cataracts and defer proper retinal evaluation for several months. We reviewed our records to determine the natural history of those SRNVMs which on initial IVFA either originated or extended into the foveal portion of the macula. Our results clearly indicate that treatment must be undertaken early in the course of this disease to maintain useful visual function for as long as possible.
在年龄相关性黄斑变性病程中，当通过静脉荧光血管造影（IVFA）确定存在视网膜下新生血管膜（SRNVM）时，视觉预后会突然改变。已意识到这种情况的患者可能会注意到阿姆斯勒方格表上的变形，并在症状出现数天内报告。不幸的是，大多数患者要么没有注意到中心视力的早期变化，要么错误地将这些症状归因于白内障的发展，并将适当的视网膜评估推迟数月。我们回顾了我们的记录，以确定那些在初次IVFA时起源于或扩展至黄斑中心凹部分的SRNVM的自然病程。我们的结果清楚地表明，必须在这种疾病的早期进行治疗，以尽可能长时间地维持有用的视觉功能。
