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咽鼓管功能障碍行鼻咽部镭照射后的死亡率。

Mortality after nasopharyngeal radium irradiation for eustachian tube dysfunction.

作者信息

Verduijn P G, Hayes R B, Looman C, Habbema J D, van der Maas P J

机构信息

Department of Otolaryngology, Hospital of Sittard, The Netherlands.

出版信息

Ann Otol Rhinol Laryngol. 1989 Nov;98(11):839-44. doi: 10.1177/000348948909801101.

Abstract

Cause-specific mortality of 2,510 persons treated before 1965 by nasopharyngeal radium irradiation (average exposure, 1,200 mg/min), followed to 1985, was compared to that of 2,199 nonexposed comparison subjects. No excess was found for the exposed group in overall mortality, cancer mortality, or in mortality of cancer of specific sites. A marginal excess (p = .07) of malignancies of the lymphatic and hematopoietic system was noted in exposed males only. Only one brain cancer (0.2 per 10(4) person-years) was identified in the exposed group, and two (10.3 per 10(4) person-years) in the nonexposed group.

摘要

对1965年前接受鼻咽镭照射(平均暴露量为1200毫克/分钟)并随访至1985年的2510名患者的特定病因死亡率,与2199名未暴露的对照对象进行了比较。在暴露组中,未发现总死亡率、癌症死亡率或特定部位癌症死亡率有过高情况。仅在暴露男性中发现淋巴和造血系统恶性肿瘤有轻微过高(p = 0.07)。暴露组仅发现1例脑癌(每104人年0.2例),未暴露组发现2例(每104人年10.3例)。

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