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胰岛素治疗的日本患者非严重低血糖的糖尿病管理及日常功能负担

Diabetes management and daily functioning burden of non-severe hypoglycemia in Japanese people treated with insulin.

作者信息

Ohashi Yasuo, Wolden Michael L, Hyllested-Winge Jacob, Brod Meryl

机构信息

Department of Integrated Science and Engineering for Sustainable Society, Chuo University, Hachioji, Tokyo, Japan.

Novo Nordisk A/S, Søborg, Denmark.

出版信息

J Diabetes Investig. 2017 Nov;8(6):776-782. doi: 10.1111/jdi.12642. Epub 2017 Apr 3.

Abstract

AIMS/INTRODUCTION: The present study investigated the impact of non-severe hypoglycemic events (NSHE) on patients' diabetes management, daily functioning and well-being.

MATERIALS AND METHODS

A survey assessing the impact of NSHEs was completed by insulin-treated Japanese people with diabetes, aged ≥20 years with self-reported diabetes, who had experienced at least one NSHE in the past 3 months. Survey questions captured reasons for and the length of the event, and impacts on diabetes management, daily functioning, sleep and well-being.

RESULTS

A total of 3,145 people with type 1 diabetes mellitus and type 2 diabetes mellitus were screened, of which 411 respondents were eligible. Increased glucose monitoring was reported by 57 and 54% of respondents after daytime and night-time NSHE, respectively. The average number of additional glucose monitoring tests was 2.4 and 3.0 for daytime and night-time NSHE. Among all respondents, 19% (daytime) and 16% (night-time) changed their insulin dose after an NSHE. After a daytime NSHE, 25% of respondents reported a negative impact on their daily activities or work. After a night-time NSHE, 34 and 23% of respondents reported a negative impact on sleep and next day emotional state, respectively.

CONCLUSIONS

NSHEs have a negative impact on the diabetes management, daily functioning, sleep and well-being of Japanese patients.

摘要

目的/引言:本研究调查了非严重低血糖事件(NSHE)对患者糖尿病管理、日常功能及幸福感的影响。

材料与方法

一项评估NSHE影响的调查由接受胰岛素治疗的日本糖尿病患者完成,这些患者年龄≥20岁,自我报告患有糖尿病,且在过去3个月内经历过至少一次NSHE。调查问题涉及事件的原因、时长,以及对糖尿病管理、日常功能、睡眠和幸福感的影响。

结果

共筛查了3145例1型糖尿病和2型糖尿病患者,其中411名受访者符合条件。分别有57%和54%的受访者报告在白天和夜间发生NSHE后增加了血糖监测。白天和夜间NSHE的额外血糖监测平均次数分别为2.4次和3.0次。在所有受访者中,19%(白天)和16%(夜间)在NSHE后改变了胰岛素剂量。白天发生NSHE后,25%的受访者报告其日常活动或工作受到负面影响。夜间发生NSHE后,分别有34%和23%的受访者报告睡眠和次日情绪状态受到负面影响。

结论

NSHE对日本患者的糖尿病管理、日常功能、睡眠和幸福感有负面影响。

相似文献

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The impact of non-severe hypoglycemia on quality of life in patients with type 2 diabetes.非严重低血糖对 2 型糖尿病患者生活质量的影响。
J Diabetes Complications. 2018 Apr;32(4):373-378. doi: 10.1016/j.jdiacomp.2018.01.014. Epub 2018 Jan 31.

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