间隔装置中瓣膜的压力流动特性。
Pressure flow characteristics of the valve in spacer devices.
作者信息
Sennhauser F H, Sly P D
机构信息
Department of Thoracic Medicine, Royal Children's Hospital, Melbourne, Australia.
出版信息
Arch Dis Child. 1989 Sep;64(9):1305-7. doi: 10.1136/adc.64.9.1305.
Abstract
The valve system in the mouth piece of two spacer devices was analysed. Pressures required to open and close the non-rebreathing valve were very low (less than 0.1 kPa). Inspiratory flow requirements were within physiological limits for infants' normal tidal breathing. Expiratory flow requirements varied significantly, and the flow required to prevent rebreathing from the chamber may exceed the physiological flow limits for normal tidal breathing.
摘要
对两种储雾罐装置咬嘴中的阀门系统进行了分析。打开和关闭非重复呼吸阀所需的压力非常低（小于0.1千帕）。吸气流量要求在婴儿正常潮式呼吸的生理限度内。呼气流量要求差异很大，防止从储气室重复呼吸所需的流量可能超过正常潮式呼吸的生理流量限度。
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本文引用的文献
1
Pulmonary mechanics in early infancy. Subclinical grunting in low-birth-weight infants.早期婴儿的肺力学。低体重婴儿的亚临床呻吟。
Pediatr Res. 1981 Jul;15(7):979-84. doi: 10.1203/00006450-198107000-00001.
2
Bronchodilators for wheezy infants?用于喘息婴儿的支气管扩张剂？
Arch Dis Child. 1984 Jan;59(1):84-7. doi: 10.1136/adc.59.1.84.
3
A method for ventilatory measurements in subjects 1 month--5 years of age: Normal results and observations in disease.1至5岁儿童通气测量方法：正常结果及疾病观察
Pediatr Res. 1970 Mar;4(2):165-74. doi: 10.1203/00006450-197003000-00007.
4
Oropharyngeal deposition and delivery aspects of metered-dose inhaler aerosols.定量吸入气雾剂的口咽沉积与递送方面
Am Rev Respir Dis. 1987 Jan;135(1):157-64. doi: 10.1164/arrd.1987.135.1.157.
5
Tidal pressure/volume and flow/volume respiratory loop patterns in human neonates.人类新生儿的潮气量/压力和流速/容量呼吸环模式。
Clin Sci Mol Med. 1978 Mar;54(3):257-64. doi: 10.1042/cs0540257.
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