9岁患者咪达唑仑戒断所致紧张症的病例报告。

Case Report of Midazolam Withdrawal-Induced Catatonia in a 9-Year-Old Patient.

作者信息

Duncan-Azadi Cassandra R, Johnson Peter N, Gormley Andrew

机构信息

From the Departments of *Anesthesiology; †Pharmacy: Clinical and Administrative Sciences; and ‡Pediatrics, Critical Care, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

出版信息

A A Case Rep. 2017 May 1;8(9):242-245. doi: 10.1213/XAA.0000000000000482.

DOI:10.1213/XAA.0000000000000482

PMID:28181946

Abstract

Benzodiazepine withdrawal-induced catatonia is a rare phenomenon in the adult population and has never been reported in a pediatric patient. We present a 9-year-old boy who exhibited catatonia symptoms following discontinuation of a midazolam infusion in the pediatric intensive care unit. The pediatric anesthesia acute pain team was consulted. When the patient's altered mental status could not otherwise be explained, benzodiazepine withdrawal-induced catatonia was considered. A dose of 2 mg intravenous lorazepam was given and the patient's symptoms dramatically improved within 5 minutes of administration. The patient was successfully treated with an oral diazepam taper.

摘要

苯二氮䓬戒断所致紧张症在成人中是一种罕见现象，在儿科患者中从未有过报道。我们报告一名9岁男孩，他在儿科重症监护病房停用咪达唑仑输注后出现紧张症症状。咨询了儿科麻醉急性疼痛小组。当患者的精神状态改变无法用其他原因解释时，考虑为苯二氮䓬戒断所致紧张症。给予2毫克静脉注射劳拉西泮，给药后5分钟内患者症状显著改善。患者通过口服地西泮逐渐减量成功治愈。