Poflee Sandhya V, Bode Anjali N, Chavarkar Sneha, Umap Pradeep S
Department of Pathology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
J Cytol. 2017 Jan-Mar;34(1):53-55. doi: 10.4103/0970-9371.197621.
Myofibromatosis (MFS) was recognized as a distinct form of childhood fibromatosis. Infantile myofibromatosis (IMF) is now identified as a solitary or multicentric tumor that predominantly occurs in neonates and infants. The adult counterpart of IMF, though of rare occurrence, is identified and is known as MFS. Morphological diagnosis of MFS is made by histopathological examination of the biopsy or surgically excised mass and confirmed on the basis of specific immunoprofile. We report a case of multicentric MFS occurring in an adolescent in whom diagnosis was suggested on the basis of fine needle aspiration cytology (FNAC) that avoided surgical excision of multiple nodules. The diagnosis was later confirmed on histopathological study and contributory immunohistochemical markers. Details of the clinical features and cytological diagnosis of the case are provided to diminish the paucity of available literature on FNAC diagnosis of the rare disease.
肌纤维瘤病（MFS）被认为是儿童纤维瘤病的一种独特形式。婴儿肌纤维瘤病（IMF）现在被确定为一种主要发生于新生儿和婴儿的单发或多中心肿瘤。IMF的成人对应疾病虽然罕见，但已被识别，称为MFS。MFS的形态学诊断通过对活检或手术切除肿块进行组织病理学检查，并根据特定免疫表型得以证实。我们报告一例发生于青少年的多中心MFS病例，该病例通过细针穿刺细胞学检查（FNAC）做出诊断，避免了对多个结节进行手术切除。诊断随后通过组织病理学研究及相关免疫组化标记得以证实。提供该病例的临床特征及细胞学诊断细节，以弥补关于这种罕见疾病FNAC诊断的现有文献的不足。
