[Morphological criteria of the acuity of peritonitis during treatment by staged cleansing irrigations of the abdominal cavity].

56 biopsies of the parietal peritoneum from 28 patients with diffuse purulent peritonitis treated with periodical irrigations of the abdominal cavity. The goal of the study was to determine histological criteria of the peritonitis course in order to establish the earliest time for hermetic closure of the abdominal cavity. It is found that the abdominal cavity irrigations--when the cause of the peritonitis is eliminated--improve the microcirculation, facilitate the development of the granulation tissue, result in the shift of cell reactions; in other words, the reparative-resorptive process dominate the destructive-inflammatory ones. The hermetic closure of the abdominal cavity can be performed without waiting for the complete morphological restoration of the peritoneum; the absence of the mesothelium and the presence of the necrotic foci may not be contraindications. It is sufficient to establish the lack of the progression of the disease (absence of the microcirculation disturbances, the cessation of the polynuclear migration beyond the vascular wall, the appearance of numerous macrophages and granulation tissue. The absence of the complications during 1.5 year allows one to suggest the complete morphological restoration of the peritoneum, after the hermetic closure of the cavity.