Research Department, Vestre Viken Hospital Trust, Drammen, Norway.
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Psychiatry Clin Neurosci. 2017 May;71(5):336-345. doi: 10.1111/pcn.12513. Epub 2017 Mar 16.
The MATRICS Consensus Cognitive Battery (MCCB) assesses seven cognitive domains with 10 subtests. This domain structure has not been demonstrated. Three factors have been produced in US samples. We examined the dimensional structure of the Norwegian MCCB. In addition, we studied the contribution of each subtest to the battery sum score.
The participants were 131 patients with schizophrenia spectrum disorders and 300 healthy controls. Their Norwegian MCCB test scores were subject to exploratory and confirmatory factor analysis and regression analysis.
The theoretical MCCB factor structure was not shown. In the patient group, three-factor and two-factor models had acceptable fit. In both groups, the Symbol Coding, Spatial Span, Letter-Number Span, and Visual Learning subtests contributed most to the sum score.
The theoretical domain structure of the MCCB could not be demonstrated in these Norwegian participants. Consonant with US studies, models with three and two factors had mediocre fit, and in the schizophrenia spectrum disorder group only. In both groups, the subtests Symbol Coding, Working Memory, and Learning were the most sensitive in tapping general neurocognitive performance, supporting US results. We conclude that in both Norway and the USA, the MCCB generates the same cognitive domains through factor analysis, but that these domains are not the ones suggested by the MATRICS project.
MATRICS 共识认知电池 (MCCB) 用 10 个分量表评估 7 个认知域。该域结构尚未得到证实。在美国样本中产生了三个因素。我们检验了挪威 MCCB 的维度结构。此外，我们还研究了每个分量表对电池总分的贡献。
参与者为 131 名精神分裂症谱系障碍患者和 300 名健康对照者。他们的挪威 MCCB 测试分数进行了探索性和验证性因素分析和回归分析。
理论上的 MCCB 因子结构没有显示出来。在患者组中，三因素和两因素模型具有可接受的拟合度。在两组中，符号编码、空间广度、字母数字广度和视觉学习分量表对总分的贡献最大。
在这些挪威参与者中，无法证明 MCCB 的理论域结构。与美国的研究一致，三因素和两因素模型的拟合度中等，且仅在精神分裂症谱系障碍组中。在两组中，符号编码、工作记忆和学习这三个分量表最能敏感地反映出一般的神经认知表现，支持美国的研究结果。我们的结论是，在挪威和美国，MCCB 通过因子分析产生相同的认知域，但这些域不是 MATRICS 项目所建议的域。
