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减少人工耳蜗同步配对刺激中的相互作用。

Reducing interaction in simultaneous paired stimulation with CI.

作者信息

Vellinga Dirk, Bruijn Saskia, Briaire Jeroen J, Kalkman Randy K, Frijns Johan H M

机构信息

ENT-Department, Leiden University Medical Centre, Leiden, The Netherlands.

出版信息

PLoS One. 2017 Feb 9;12(2):e0171071. doi: 10.1371/journal.pone.0171071. eCollection 2017.

Abstract

In this study simultaneous paired stimulation of electrodes in cochlear implants is investigated by psychophysical experiments in 8 post-lingually deaf subjects (and one extra subject who only participated in part of the experiments). Simultaneous and sequential monopolar stimulation modes are used as references and are compared to channel interaction compensation, partial tripolar stimulation and a novel sequential stimulation strategy named phased array compensation. Psychophysical experiments are performed to investigate both the loudness integration during paired stimulation at the main electrodes as well as the interaction with the electrode contact located halfway between the stimulating pair. The study shows that simultaneous monopolar stimulation has more loudness integration on the main electrodes and more interaction in between the electrodes than sequential stimulation. Channel interaction compensation works to reduce the loudness integration at the main electrodes, but does not reduce the interaction in between the electrodes caused by paired stimulation. Partial tripolar stimulation uses much more current to reach the needed loudness, but shows the same interaction in between the electrodes as sequential monopolar stimulation. In phased array compensation we have used the individual impedance matrix of each subject to calculate the current needed on each electrode to exactly match the stimulation voltage along the array to that of sequential stimulation. The results show that the interaction in between the electrodes is the same as monopolar stimulation. The strategy uses less current than partial tripolar stimulation, but more than monopolar stimulation. In conclusion, the paper shows that paired stimulation is possible if the interaction is compensated.

摘要

在本研究中,通过对8名语后聋受试者(以及一名仅参与部分实验的额外受试者)进行心理物理学实验,研究了人工耳蜗电极的同步配对刺激。同步和顺序单极刺激模式用作参考,并与通道相互作用补偿、部分三极刺激以及一种名为相控阵补偿的新型顺序刺激策略进行比较。进行心理物理学实验以研究配对刺激期间主电极处的响度整合以及与位于刺激对中间位置的电极触点之间的相互作用。研究表明,与顺序刺激相比,同步单极刺激在主电极上具有更多的响度整合,并且电极之间的相互作用更多。通道相互作用补偿有助于减少主电极处的响度整合,但不会减少配对刺激引起的电极之间的相互作用。部分三极刺激需要使用更多电流才能达到所需响度,但电极之间的相互作用与顺序单极刺激相同。在相控阵补偿中,我们使用了每个受试者的个体阻抗矩阵来计算每个电极上所需的电流,以使沿阵列的刺激电压与顺序刺激的电压精确匹配。结果表明,电极之间的相互作用与单极刺激相同。该策略使用的电流比部分三极刺激少,但比单极刺激多。总之,本文表明,如果相互作用得到补偿,配对刺激是可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9b9/5300223/ed98dc01de53/pone.0171071.g001.jpg

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