McDonnell P J, Schofield O M, Spalton D J, Eady R A
Department of Ophthalmology, United Medical School, St Thomas' Hospital, London, England.
Arch Ophthalmol. 1989 Nov;107(11):1635-7. doi: 10.1001/archopht.1989.01070020713034.
The ocular findings in a group of five patients with the nonlethal form of junctional epidermolysis bullosa are presented. A history of recurrent corneal erosion and the presence of corneal scarring were the most common findings. We discuss the possible mechanisms of the ocular changes and describe how the recent application of monoclonal antibody probes to components of the basement membrane are helping to elucidate the basic defect in this condition.
本文报告了一组五例非致死型交界性大疱性表皮松解症患者的眼部检查结果。复发性角膜糜烂病史和角膜瘢痕形成是最常见的检查结果。我们讨论了眼部病变的可能机制，并描述了单克隆抗体探针最近应用于基底膜成分如何有助于阐明这种疾病的基本缺陷。
