Canfield P J, O'Neill M E, Smith E F
Department of Veterinary Pathology, University of Sydney, New South Wales.
Aust Vet J. 1989 Sep;66(9):269-72. doi: 10.1111/j.1751-0813.1989.tb13949.x.
Haematological and biochemical investigations were performed on 14 koalas with uncomplicated cystitis, 8 with complicated cystitis, 8 with conjunctivitis, 8 with lymphosarcoma, and 14 with miscellaneous diseases. Changes were limited and inconsistent in individual koalas with uncomplicated cystitis and conjunctivitis. In contrast, individual koalas with complicated cystitis were more likely to have anaemia, leukocytosis due to neutrophilia, hypoproteinaemia due to hypoalbuminaemia, and azotaemia due to elevated urea concentration. Although these changes were non-specific they did allow assessment of prognosis for survival and response to treatment. Koalas with lymphosarcoma were invariably anaemic, leukaemic, azotaemic and hypoalbuminaemic. Elevated enzymes (aspartate transaminase [AST]. lactate dehydrogenase [LD] and gamma glutamyl transferase [GGT]) were more common in koalas with lymphosarcoma. Koalas affected by miscellaneous conditions showed variable changes but once again anaemia, leukocytosis, azotaemia, elevated AST and LD, and hypoalbuminaemia were not uncommon. On the basis of these findings a minimal profile is suggested for the investigation of sick koalas and would include haematocrit, total and differential leukocyte counts, urea, total protein and albumin concentrations and AST, GGT and LD activities.
对14只患有单纯性膀胱炎、8只患有复杂性膀胱炎、8只患有结膜炎、8只患有淋巴肉瘤以及14只患有其他杂症的考拉进行了血液学和生化检查。患有单纯性膀胱炎和结膜炎的个体考拉的变化有限且不一致。相比之下，患有复杂性膀胱炎的个体考拉更有可能出现贫血、因中性粒细胞增多导致的白细胞增多、因白蛋白减少导致的低蛋白血症以及因尿素浓度升高导致的氮血症。虽然这些变化不具有特异性，但它们确实有助于评估生存预后和对治疗的反应。患有淋巴肉瘤的考拉总是贫血、白血病、氮血症和低白蛋白血症。酶（天冬氨酸转氨酶[AST]、乳酸脱氢酶[LD]和γ-谷氨酰转移酶[GGT]）升高在患有淋巴肉瘤的考拉中更为常见。受其他杂症影响的考拉表现出各种变化，但贫血、白细胞增多、氮血症、AST和LD升高以及低白蛋白血症再次并不罕见。基于这些发现，建议对患病考拉进行检查的最小项目包括血细胞比容、白细胞总数和分类计数、尿素、总蛋白和白蛋白浓度以及AST、GGT和LD活性。
