sfinx：用于从亲和纯化-质谱数据集消除假阳性的 R 包。
sfinx: an R package for the elimination of false positives from affinity purification-mass spectrometry datasets.
机构信息
VIB Medical Biotechnology Center, A. Baertsoenkaai 3, Ghent, Belgium.
Department of Biochemistry, Ghent University, Ghent, Belgium.
出版信息
Bioinformatics. 2017 Jun 15;33(12):1902-1904. doi: 10.1093/bioinformatics/btx076.
SUMMARY
We describe sfinx, an R package providing access to the straightforward filtering index (SFINX) for the separation of true positive from false positive protein interactions in affinity purification - mass spectrometry datasets. This package maintains the reliability and user-friendliness of the SFINX web site interface but is faster, unlimited in input size, and can be run locally within R.
AVAILABILITY AND IMPLEMENTATION
The sfinx R package is available for download at the comprehensive R archive network (CRAN) https://cran.r-project.org/web/packages/sfinx/ under the Apache License 2.0.
CONTACT
sven.eyckerman@vib-ugent.be or kevin.titeca@gmail.com.
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
摘要
我们描述了 sfinx，这是一个 R 包，提供了对简单过滤指数（SFINX）的访问，用于在亲和纯化-质谱数据集的真实阳性和假阳性蛋白质相互作用中进行分离。该软件包保持了 SFINX 网站界面的可靠性和用户友好性，但速度更快，输入大小不受限制，并且可以在 R 内部本地运行。
可用性和实现
sfinx R 包可在综合 R 档案网络（CRAN）https://cran.r-project.org/web/packages/sfinx/ 上下载，根据 Apache License 2.0 许可。
联系方式
sven.eyckerman@vib-ugent.be 或 kevin.titeca@gmail.com。
补充信息
补充数据可在生物信息学在线获得。
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