Dams Judith, König Hans-Helmut, Bleibler Florian, Hoyer Jürgen, Wiltink Jörg, Beutel Manfred E, Salzer Simone, Herpertz Stephan, Willutzki Ulrike, Strauß Bernhard, Leibing Eric, Leichsenring Falk, Konnopka Alexander
Department of Health Economics and Health Services Research, Hamburg Center for Health Economics (HCHE), University Medical Center Hamburg-Eppendorf, Germany.
Department of Health Economics and Health Services Research, Hamburg Center for Health Economics (HCHE), University Medical Center Hamburg-Eppendorf, Germany.
J Affect Disord. 2017 Apr 15;213:23-29. doi: 10.1016/j.jad.2017.01.041. Epub 2017 Feb 2.
Social anxiety disorder is one of the most frequent mental disorders. It is often associated with mental comorbidities and causes a high economic burden. The aim of our analysis was to estimate the excess costs of patients with social anxiety disorder compared to persons without anxiety disorder in Germany.
Excess costs of social anxiety disorder were determined by comparing two data sets. Patient data came from the SOPHO-NET study A1 (n=495), whereas data of persons without anxiety disorder originated from a representative phone survey (n=3213) of the general German population. Missing data were handled by "Multiple Imputation by Chained Equations". Both data sets were matched using "Entropy Balancing". Excess costs were calculated from a societal perspective for the year 2014 using general linear regression with a gamma distribution and log-link function. Analyses considered direct costs (in- and outpatient treatment, rehabilitation, and professional and informal care) and indirect costs due to absenteeism from work.
Total six-month excess costs amounted to 451€ (95% CI: 199€-703€). Excess costs were mainly caused by indirect excess costs due to absenteeism from work of 317€ (95% CI: 172€-461€), whereas direct excess costs amounted to 134€ (95% CI: 110€-159€).
Costs for medication, unemployment and disability pension was not evaluated.
Social anxiety disorder was associated with statistically significant excess costs, in particular due to indirect costs. As patients in general are often unaware of their disorder or its severity, awareness should be strengthened. Prevention and early treatment might reduce long-term indirect costs.
社交焦虑障碍是最常见的精神障碍之一。它常与精神共病相关,并造成高昂的经济负担。我们分析的目的是估计德国社交焦虑障碍患者与无焦虑障碍者相比的额外费用。
通过比较两个数据集确定社交焦虑障碍的额外费用。患者数据来自SOPHO-NET研究A1(n = 495),而无焦虑障碍者的数据来自对德国普通人群的代表性电话调查(n = 3213)。缺失数据采用“链式方程多重插补”处理。两个数据集使用“熵平衡”进行匹配。从社会角度出发,采用具有伽马分布和对数链接函数的一般线性回归计算2014年的额外费用。分析考虑了直接费用(住院和门诊治疗、康复以及专业和非正式护理)和因缺勤导致的间接费用。
六个月的总额外费用为451欧元(95%置信区间:199欧元 - 703欧元)。额外费用主要由因缺勤导致的间接额外费用317欧元(95%置信区间:172欧元 - 461欧元)引起,而直接额外费用为134欧元(95%置信区间:110欧元 - 159欧元)。
未评估药物、失业和残疾抚恤金的费用。
社交焦虑障碍与具有统计学意义的额外费用相关,特别是由于间接费用。由于一般患者往往未意识到自己的疾病或其严重程度,应加强认识。预防和早期治疗可能会降低长期间接费用。