Blaich Annette, Frei Reno, Castellano Carine, Kiessling Christine, Geschke Angelika, Rentsch Katharina M, Egli Adrian
Division of Clinical Microbiology, University Hospital Basel, Basel, Switzerland.
Division of Clinical Microbiology, University Hospital Basel, Basel, Switzerland.
J Microbiol Methods. 2017 Apr;135:63-65. doi: 10.1016/j.mimet.2017.02.004. Epub 2017 Feb 10.
A novel immunoassay for Clostridium difficile glutamate dehydrogenase (GDH) and toxin A&B (LIAISON, DiaSorin) was compared to another GDH assay (Alere), PCR and toxigenic culture. The GDH-DiaSorin is slightly more sensitive than the GDH-Alere. Sensitivity of the Toxin-Diasorin test is in accordance to the sensitivity of other immunoassays in literature.
将一种用于艰难梭菌谷氨酸脱氢酶（GDH）和毒素A&B的新型免疫测定法（LIAISON，索林集团）与另一种GDH测定法（Alere）、聚合酶链反应（PCR）和产毒培养法进行了比较。索林集团的GDH测定法比Alere的GDH测定法稍敏感一些。索林集团毒素检测的灵敏度与文献中其他免疫测定法的灵敏度一致。
