Lüke J, Grisanti S, Tura A
Klinik für Augenheilkunde, Universitätsklinikum Schleswig-Holstein, Lübeck.
Klin Monbl Augenheilkd. 2017 Jul;234(7):868-873. doi: 10.1055/s-0042-124513. Epub 2017 Feb 13.
The detection and characterisation of circulating melanoma cells (CMC) is a non-invasive procedure with a low complication rate and can potentially distinguish choroidal nevi from uveal melanomas and help to initiate early adequate therapy. It has the perspective to select and monitor treatment. This technique may lead to new insights into the metastasis process itself and help to detect specific targets for future therapies. This article introduces the different techniques for CMC detection; their potentials and limitations are discussed.
循环黑色素瘤细胞(CMC)的检测与表征是一种并发症发生率低的非侵入性检查方法,它有可能区分脉络膜痣和葡萄膜黑色素瘤,并有助于启动早期充分治疗。它有望用于选择和监测治疗。该技术可能会为转移过程本身带来新的见解,并有助于检测未来治疗的特定靶点。本文介绍了检测CMC的不同技术,并讨论了它们的潜力和局限性。