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热带糖尿病手综合征:一例报告。

Tropical diabetic hand syndrome: a case report.

作者信息

Yeika Eugene Vernyuy, Tchoumi Tantchou Jacques Cabral, Foryoung Joyce Bei, Tolefac Paul Nkemtendong, Efie Derrick Tembi, Choukem Siméon Pierre

机构信息

Saint Elizabeth Catholic General Hospital and Cardiac Centre Shisong, Kumbo, Cameroon.

Clinical Research Education Networking and Consultancy, Douala, Cameroon.

出版信息

BMC Res Notes. 2017 Feb 13;10(1):94. doi: 10.1186/s13104-017-2405-3.

Abstract

BACKGROUND

Tropical diabetic hand syndrome describes a complex hand sepsis affecting patients with diabetes across the tropics and often results from a trivial hand trauma. The clinical presentation of this syndrome is variable and ranges from localised swelling and cellulitis, with or without ulceration of the hand to progressive fulminant hand sepsis, and gangrene affecting the entire limb which may be fatal. Tropical diabetic hand syndrome could lead to permanent disability and death as a result of delay in presentation, late diagnosis and late medical and surgical intervention. This indexed case acts as an eye opener for physicians to the existence of this hand sepsis.

CASE PRESENTATION

We report the case of a 57 year-old black African female diabetic who was referred to our centre for the management of a suppurating ulcer and swelling of the left hand of two weeks duration. On examination and work-up, the patient was found to have Lawal Group III left diabetic hand syndrome and was managed with parenteral antibiotics, radical debridement and the hand was eventually amputated. She died 7 days following amputation from overwhelming sepsis.

CONCLUSION

Though tropical diabetic hand syndrome is a relatively rare complication of diabetes, it can be fatal as in this case report. Early diagnosis and proper management would yield better outcome. Initial management should include aggressive intravenous broad-spectrum antibiotics with anaerobic coverage. Classification of tropical diabetic hand syndrome will assist physicians and surgeons in decision making, proper management and easy communication.

摘要

背景

热带糖尿病手综合征描述的是一种影响热带地区糖尿病患者的复杂手部脓毒症,通常由轻微的手部创伤引发。该综合征的临床表现多样,从局部肿胀和蜂窝织炎(手部有无溃疡)到进行性暴发性手部脓毒症,再到影响整个肢体的坏疽,可能会导致死亡。由于就诊延迟、诊断较晚以及医疗和手术干预不及时,热带糖尿病手综合征可能导致永久性残疾和死亡。本索引病例为医生认识这种手部脓毒症敲响了警钟。

病例介绍

我们报告了一名57岁的非洲黑人女性糖尿病患者的病例,她因左手化脓性溃疡和肿胀两周被转诊至我们中心。经检查和评估,发现该患者患有拉瓦尔III级左糖尿病手综合征,接受了静脉注射抗生素、彻底清创治疗,最终手部被截肢。截肢7天后,她因严重脓毒症死亡。

结论

尽管热带糖尿病手综合征是糖尿病相对罕见的并发症,但如本病例报告所示,它可能是致命的。早期诊断和妥善管理会取得更好的结果。初始治疗应包括使用覆盖厌氧菌的强效静脉注射广谱抗生素。热带糖尿病手综合征的分类将有助于医生和外科医生进行决策、妥善管理并便于沟通。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/972e/5307844/be4ac8473007/13104_2017_2405_Fig1_HTML.jpg

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