通用 CAR T 细胞疗法治疗白血病。
Universal CAR T Cells Treat Leukemia.
出版信息
Cancer Discov. 2017 Apr;7(4):342. doi: 10.1158/2159-8290.CD-NB2017-023. Epub 2017 Feb 13.
Abstract
Two infants with relapsed, refractory B-cell acute lymphoblastic leukemia went into complete remission after being treated with CD19-targeting CAR T cells derived from an unmatched donor. The study is the first to demonstrate that a universal form of CAR T-cell therapy can be safely utilized.
摘要
两名复发、难治性 B 细胞急性淋巴细胞白血病患儿接受了来自非匹配供体的靶向 CD19 的嵌合抗原受体 T 细胞（CAR T 细胞）治疗后达到完全缓解。该研究首次证明了一种通用形式的 CAR T 细胞疗法可以安全使用。
Zotero 插件