Sámal M, Dienstbier Z
Bratisl Lek Listy. 1989 Oct;90(10):732-9.
Factor analysis allows to break up dynamic radionuclide studies into constituent parts corresponding to individual compartments of the distribution space of the radiopharmaceutical in the body. Compartment structure is reflected by factor image and its dynamics is shown by factor time activity curves. The method overcomes the drawbacks of other data processing methods in dynamic scintigraphy by its objectiveness and by distinguishing the projection overlap of tissues with different dynamics. The demands on both the patient and personnel are the same as in standard procedures, yet this method extracts more information from the results of the examination. Higher diagnostic accuracy was reported especially in nuclear cardiology and nephrology. A short survey of clinical applications of factor analysis reported over the years 1982-1988 is presented.
因子分析能够将动态放射性核素研究分解为与放射性药物在体内分布空间的各个独立隔室相对应的组成部分。隔室结构由因子图像反映,其动力学由因子时间-活度曲线显示。该方法克服了动态闪烁显像中其他数据处理方法的缺点,具有客观性,并且能够区分具有不同动力学的组织的投影重叠。对患者和工作人员的要求与标准程序相同,但该方法能从检查结果中提取更多信息。尤其在核心脏病学和肾脏病学领域,报告显示其具有更高的诊断准确性。本文对1982年至1988年期间报道的因子分析临床应用进行了简要综述。