Ihunwo Amadi O, Tembo Lackson H, Dzamalala Charles
School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Neural Regen Res. 2016 Dec;11(12):1869-1883. doi: 10.4103/1673-5374.195278.
The phenomenon of adult neurogenesis is now an accepted occurrence in mammals and also in humans. At least two discrete places house stem cells for generation of neurons in adult brain. These are olfactory system and the hippocampus. In animals, newly generated neurons have been directly or indirectly demonstrated to generate a significant amount of new neurons to have a functional role. However, the data in humans on the extent of this process is still scanty and such as difficult to comprehend its functional role in humans. This paper explores the available data on as extent of adult hippocampal neurogenesis in humans and makes comparison to animal data.
成体神经发生现象如今在哺乳动物乃至人类中都已被认可。成体大脑中至少有两个不同的部位存在用于生成神经元的干细胞。这些部位是嗅觉系统和海马体。在动物身上,新生成的神经元已被直接或间接地证明能产生大量具有功能作用的新神经元。然而,关于人类这一过程的程度的数据仍然很少,因此很难理解其在人类中的功能作用。本文探讨了关于人类成体海马体神经发生程度的现有数据,并与动物数据进行了比较。