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对比剂肾病;近期研究发现

Contrast induced nephropathy; recent findings.

作者信息

Mardani Saeed, Nasri Parto, Tavakoli Maryam

机构信息

Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.

School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

J Nephropharmacol. 2013 Jul 1;2(2):27-30. eCollection 2013.

PMID:28197441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5297549/
Abstract

Contrast induced nephropathy is one cause of acute renal failure. Contrast induced nephropathy is the third most common cause of hospital-acquired acute renal failure. The incidence of contrast induced nephropathy in the general population is 0.6% to 2.3%, but when focusing on specific high-risk patients the incidence can increase to more than 40%. Studies suggest that intravenous hydration is the most effective strategy to prevent contrast induced nephropathy. Hydration is inexpensive and is usually risk-free. Administration of optimal fluids before and after the contrast procedure allows for increased urine output and improved outcomes.

摘要

对比剂肾病是急性肾衰竭的一个病因。对比剂肾病是医院获得性急性肾衰竭的第三大常见病因。普通人群中对比剂肾病的发病率为0.6%至2.3%,但聚焦于特定高危患者时,发病率可增至40%以上。研究表明,静脉补液是预防对比剂肾病最有效的策略。补液成本低且通常无风险。在进行对比剂检查之前和之后给予最佳液体可增加尿量并改善预后。

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本文引用的文献

1
Role of reactive oxygen species in pathogenesis of radiocontrast-induced nephropathy.活性氧在放射性造影剂所致肾病发病机制中的作用
Biomed Res Int. 2013;2013:868321. doi: 10.1155/2013/868321. Epub 2013 Dec 29.
2
Adverse reactions to iodinated contrast media.碘化造影剂的不良反应。
Int J Angiol. 2013 Sep;22(3):149-54. doi: 10.1055/s-0033-1348885.
3
A plan to reduce contrast induced nephropathy.一项减少造影剂肾病的计划。
Catheter Cardiovasc Interv. 2013 Nov 15;82(6):898. doi: 10.1002/ccd.25208.
4
Why is diabetes mellitus a risk factor for contrast-induced nephropathy?为什么糖尿病是对比剂肾病的一个危险因素?
Biomed Res Int. 2013;2013:123589. doi: 10.1155/2013/123589. Epub 2013 Nov 21.
5
Incidence of contrast-induced nephropathy in hospitalised patients with cancer.癌症住院患者对比剂肾病的发生率。
Eur Radiol. 2014 Jan;24(1):184-90. doi: 10.1007/s00330-013-2996-6. Epub 2013 Sep 25.
6
Statins against drug-induced nephrotoxicity.他汀类药物防治药物性肾毒性。
J Pharm Pharm Sci. 2013;16(4):588-608. doi: 10.18433/j3t30f.
7
Meta-analysis of the effect of automated contrast injection devices versus manual injection and contrast volume on risk of contrast-induced nephropathy.自动化对比剂注射装置与手动注射和对比剂用量对对比剂肾病风险影响的荟萃分析。
Am J Cardiol. 2014 Jan 1;113(1):49-53. doi: 10.1016/j.amjcard.2013.08.040. Epub 2013 Oct 3.
8
About contrast-induced nephropathy.关于对比剂肾病。
Anadolu Kardiyol Derg. 2013 Nov;13(7):719-20. doi: 10.5152/akd.2013.241. Epub 2013 Oct 23.
9
Increased serum asymmetric dimethylarginine level is an independent predictor of contrast-induced nephropathy.血清不对称二甲基精氨酸水平升高是造影剂肾病的独立预测指标。
Turk Kardiyol Dern Ars. 2013 Oct;41(7):581-8. doi: 10.5543/tkda.2013.88403.
10
Contrast-induced nephropathy: pathophysiology and preventive strategies.对比剂肾病:病理生理学与预防策略
Crit Care Nurse. 2013 Feb;33(1):37-46. doi: 10.4037/ccn2013680.