Tomov T, Iliev Ia, Todorov B, Georgiev P
Vet Med Nauki. 1987;24(4):27-36.
Studied was the effect of thyroid hormones on the nonspecific resistance and the milk productivity of ruminant animals in the conditions of hypodynamia and in various functional conditions of the thyroid gland. Both the removal of the thyroid gland (thyroidectomy) and the hypofunction of the gland (as induced by ammonium perchlorate at 10 mg/kg body mass) were accompanied by the drop of the indices characterizing the nonspecific resistance of the animals as well as their milk productivity. The immobilization of lactating ruminant animals (hypodynamia) had a negative impact on the milk producing process, enhanced the incretion of ACTH, lowered the release of thyroid hormones (T3, T4, FT4) and decreased milk productivity, deteriorating the biologic properties of colostrum. The thyroid gland and its hormones (T4, T3) were shown to have a positive effect on milk secretion, raising the activity of the enzyme adenylate cyclase and the amount of the cyclic 3.5 cyclic adenosine monophosphate (cAMP) in the parenchymal tissue of the mammary gland.
研究了甲状腺激素在运动不足以及甲状腺各种功能状态下对反刍动物非特异性抵抗力和产奶性能的影响。摘除甲状腺（甲状腺切除术）以及甲状腺功能减退（由按体重10mg/kg的高氯酸铵诱导）均伴随着表征动物非特异性抵抗力及其产奶性能的指标下降。泌乳反刍动物的固定（运动不足）对产奶过程有负面影响，增强了促肾上腺皮质激素的分泌，降低了甲状腺激素（T3、T4、FT4）的释放并降低了产奶性能，使初乳的生物学特性恶化。甲状腺及其激素（T4、T3）对乳汁分泌具有积极作用，可提高乳腺实质组织中腺苷酸环化酶的活性以及环3,5 - 环腺苷单磷酸（cAMP）的量。
