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[儿童神经母细胞瘤和肾母细胞瘤外周血淋巴细胞分化抗原测定的临床意义]

[Clinical significance of determining differentiation antigens of peripheral blood lymphocytes in neuroblastoma and nephroblastoma in children].

作者信息

Durnov L A, Torubarova M A, Zikiriakhodzhaev D Z, Bukhny A F, Sukhanova E L

出版信息

Vopr Onkol. 1987;33(8):62-70.

PMID:2820148
Abstract

Peripheral blood lymphocytes were studied in 22 pediatric patients suffering nephroblastoma and neuroblastoma. Monoclonal antibodies were used. Failure of T-cell immunity was registered in both groups. Nephroblastoma patients revealed high levels of natural killer cells. Immunity was studied versus clinical stage, duration of disease and response. Immunocorrection modalities are discussed.

摘要

对22例患有肾母细胞瘤和神经母细胞瘤的儿科患者的外周血淋巴细胞进行了研究。使用了单克隆抗体。两组均出现T细胞免疫功能衰竭。肾母细胞瘤患者的自然杀伤细胞水平较高。针对临床分期、疾病持续时间和反应对免疫情况进行了研究。讨论了免疫纠正方式。

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