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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Wong S F, Mitchell M I, Robson V, Wilkinson R

Clin Sci Mol Med Suppl. 1978 Dec;4:301s-303s. doi: 10.1042/cs055301s.

Plasma renin activity, response to saralasin and exchangeable sodium have been measured in 43 patients with early renal disease. 2. Blood pressure was directly proportional to plasma renin activity. However, mean plasma renin activity was lower in patients with renal disease than in normal controls. 3. Blood pressure fell in response to saralasin infusion in proportion to the pre-infusion plasma renin activity. 4. Exchangeable sodium in hypertensive patients with renal disease did not exceed that in normotensive patients in contrast to earlier reports. Discrepancies may arise from the difficulty in interpreting measured exchangeable sodium in relation to body build.

对43例早期肾病患者测定了血浆肾素活性、对沙拉新的反应以及可交换钠。2. 血压与血浆肾素活性成正比。然而，肾病患者的平均血浆肾素活性低于正常对照组。3. 输注沙拉新后血压下降，下降幅度与输注前血浆肾素活性成比例。4. 与早期报告相反，肾病高血压患者的可交换钠并未超过血压正常患者。差异可能源于在解释与体型相关的测得的可交换钠时存在困难。

Wong S F, Mitchell M I, Robson V, Wilkinson R

Clin Sci Mol Med Suppl. 1978 Dec;4:301s-303s. doi: 10.1042/cs055301s.

Plasma renin activity, response to saralasin and exchangeable sodium have been measured in 43 patients with early renal disease. 2. Blood pressure was directly proportional to plasma renin activity. However, mean plasma renin activity was lower in patients with renal disease than in normal controls. 3. Blood pressure fell in response to saralasin infusion in proportion to the pre-infusion plasma renin activity. 4. Exchangeable sodium in hypertensive patients with renal disease did not exceed that in normotensive patients in contrast to earlier reports. Discrepancies may arise from the difficulty in interpreting measured exchangeable sodium in relation to body build.

对43例早期肾病患者测定了血浆肾素活性、对沙拉新的反应以及可交换钠。2. 血压与血浆肾素活性成正比。然而，肾病患者的平均血浆肾素活性低于正常对照组。3. 输注沙拉新后血压下降，下降幅度与输注前血浆肾素活性成比例。4. 与早期报告相反，肾病高血压患者的可交换钠并未超过血压正常患者。差异可能源于在解释与体型相关的测得的可交换钠时存在困难。