Zhu Zezhang, Xu Leilei, Jiang Long, Sun Xu, Qiao Jun, Qian Bang-Ping, Mao Saihu, Qiu Yong
Spine Surgery, the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Clin Spine Surg. 2017 Mar;30(2):85-89. doi: 10.1097/BSD.0b013e3182a1de29.
A retrospective study to determine whether brace treatment is appropriate for adolescent idiopathic scoliosis patients with Cobb angle between 40 and 50 degrees who utterly refuse surgery.
To investigate whether it is possible to halt the curve progression of adolescent idiopathic scoliosis patients with Cobb angle between 40 and 50 degrees through bracing, and to identify factors that could influence the effectiveness of brace treatment in such patients.
Despite of the great achievements in treating patients with mild curve, bracing has been considered to be inappropriate for those with curves of >40 degrees. However, in clinical practice surgeons could encounter a series of patients who utterly refused surgery and insisted on wearing brace despite having a curve >40 degrees.
A cohort of 54 patients with Cobb angle between 40 and 50 degrees were reviewed in the current study. All the patients refused surgery at their first visit and insisted on receiving brace treatment. Each patient was followed up at an interval of 3-6 months. Variants such as initial Risser sign, initial age, sex, curve pattern, and initial curve magnitude were compared between patients with and without curve progression. A logistic regression analysis was performed to determine the independent predictors of the curve progression.
On the whole, the curve progressed in 35 patients, remained stable in 12 patients, and improved in the else 7 patients. All the patients with curve progression finally received surgical intervention. The mean grade of initial Risser sign in patients with curve progression was significantly lower than that in patients with stable or improved curve (0.3±0.8 vs. 1.2±1.4, P=0.02). In terms of sex, age, curve pattern, and curve magnitude, there were no significant differences between the 2 categories. The results of the logistic regression analysis showed that initial Risser sign of grade 0 or 1 had significant associations with the curve progression of patients with curves >40 degrees (odds ratio, 7.51, 95% confidence intervak, 1.27-24.43, P=0.02).
The effectiveness of brace treatment significantly decreases when applied to patients with curve magnitude between 40 and 50 degrees. Although a majority of these patients will inevitably undergo a surgical intervention, and thus wearing a brace may not be the best alternative to surgical intervention; there are patients who will stabilize with the brace until skeletal maturity thus warranting this option for those patients refusing surgical intervention with curves between 40 and 50 degrees.
一项回顾性研究,以确定支具治疗是否适用于Cobb角在40至50度且完全拒绝手术的青少年特发性脊柱侧凸患者。
研究对于Cobb角在40至50度的青少年特发性脊柱侧凸患者,通过支具治疗能否阻止曲线进展,并确定可能影响此类患者支具治疗效果的因素。
尽管在治疗轻度曲线患者方面取得了巨大成就,但支具治疗一直被认为不适用于曲线大于40度的患者。然而,在临床实践中,外科医生可能会遇到一系列患者,尽管曲线大于40度,但他们完全拒绝手术并坚持佩戴支具。
本研究回顾了54例Cobb角在40至50度的患者。所有患者在首次就诊时均拒绝手术,并坚持接受支具治疗。每位患者每隔3至6个月接受一次随访。比较有曲线进展和无曲线进展患者的初始Risser征、初始年龄、性别、曲线类型和初始曲线大小等变量。进行逻辑回归分析以确定曲线进展的独立预测因素。
总体而言,35例患者曲线进展,12例患者曲线保持稳定,其余7例患者曲线改善。所有曲线进展的患者最终均接受了手术干预。曲线进展患者的初始Risser征平均等级显著低于曲线稳定或改善患者(0.3±0.8对1.2±1.4,P = 0.02)。在性别、年龄、曲线类型和曲线大小方面,两组之间无显著差异。逻辑回归分析结果显示,初始Risser征为0级或1级与曲线大于40度患者的曲线进展显著相关(比值比,7.51,95%置信区间,1.27 - 24.43,P = 0.02)。
当应用于曲线大小在40至50度的患者时,支具治疗的效果显著降低。尽管这些患者中的大多数将不可避免地接受手术干预,因此佩戴支具可能不是手术干预的最佳替代方案;但仍有患者通过支具治疗直至骨骼成熟,因此对于那些拒绝手术干预且曲线在40至50度的患者,这一选择是合理的。