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硅胶棒额肌悬吊术治疗先天性上睑下垂术后复发原因分析

Analysis of the causes of recurrence after frontalis suspension using silicone rods for congenital ptosis.

作者信息

Kim Chang Yeom, Son Byeong Jae, Son Jangyup, Hong Jongill, Lee Sang Yeul

机构信息

The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.

Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine, Seoul, Korea.

出版信息

PLoS One. 2017 Feb 16;12(2):e0171769. doi: 10.1371/journal.pone.0171769. eCollection 2017.

Abstract

BACKGROUND

Silicone rod is a commonly used synthetic suspension material in frontalis suspension surgery to correct blepharoptosis. The most challenging problem and a decisive drawback of the use of silicone rod is a considerable rate of ptosis recurrence after surgery. We examined patients with recurred ptosis and assessed the physical and micromorphological properties of implanted silicone rods to determine the causative mechanisms of recurred ptosis after frontalis suspension using silicone rod.

METHODS

This is a prospective observational case series of 22 pediatric patients with recurred ptosis after frontalis suspension using silicone rods for congenital ptosis. Implanted silicone rods were observed and removed during the operation for correction of recurred ptosis. The removed silicone rods were physically and micromorphologically evaluated to determine the cause of recurrence.

RESULTS

Pretarsal fixation positions migrated upward, whereas suprabrow fixation positions migrated downward during ptosis recurrence. The breaking strength of implanted silicone rods was reduced by approximately 50% during 3 years. Cracks, debris, and loss of homogenous structure with disintegration were observed on scanning electron micrographs of implanted silicone rods in patients with recurred ptosis. Preoperative severe degree of ptosis also contributed to recurred ptosis.

CONCLUSIONS

Recurrence of ptosis after frontalis suspension using silicone rod was associated with physical changes of implanted silicone rods, including positional migration, weakened tensile strength, and micromorphological changes in combination with patients' characteristics.

摘要

背景

硅胶棒是额肌悬吊手术中常用的一种合成悬吊材料,用于矫正上睑下垂。使用硅胶棒最具挑战性的问题和决定性的缺点是术后上睑下垂复发率相当高。我们检查了上睑下垂复发的患者,并评估了植入硅胶棒的物理和微观形态特性,以确定使用硅胶棒进行额肌悬吊术后上睑下垂复发的致病机制。

方法

这是一项前瞻性观察性病例系列研究,纳入了22例因先天性上睑下垂使用硅胶棒进行额肌悬吊术后上睑下垂复发的儿科患者。在矫正复发上睑下垂的手术过程中观察并取出植入的硅胶棒。对取出的硅胶棒进行物理和微观形态评估,以确定复发原因。

结果

上睑下垂复发期间,睑板前固定位置向上迁移,而眉上固定位置向下迁移。植入的硅胶棒在3年内抗断裂强度降低了约50%。在复发上睑下垂患者植入硅胶棒的扫描电子显微镜图像上观察到有裂纹、碎片以及均匀结构丧失和崩解。术前上睑下垂的严重程度也导致了上睑下垂复发。

结论

使用硅胶棒进行额肌悬吊术后上睑下垂复发与植入硅胶棒的物理变化有关,包括位置迁移、拉伸强度减弱和微观形态变化,同时也与患者自身特征有关。

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