Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510080, China.
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.
Medicina (Kaunas). 2023 Mar 22;59(3):630. doi: 10.3390/medicina59030630.
: Previous studies on ptosis recurrence after correction surgery have tended to focus on postoperative complications, surgical methods and suspension materials, few have mentioned refractive error. This research is to investigate the potential relation between refractive error and recurrence after correction surgery in pediatric patients with simple congenital ptosis. : We conducted a retrospective analysis of data from patients with simple congenital ptosis who were treated at Zhongshan Ophthalmic Center (ZOC) between 2017 and 2020. In total, 111 eyelids of 85 patients without surgery-related complications who underwent frontalis muscle flap suspension (FMFS) for simple congenital ptosis were included. Postoperative changes in eyelid height were assessed. Cycloplegic refraction was assessed before surgery and during the follow-up period (every 3 months after surgery). Recurrence in the postoperative period was defined as a marginal reflex distance 1 (MRD1) of <1 mm. : There were 16 recurrence and 69 non-recurrence cases, with no statistically significant differences, in terms of patient age at the time of surgery, patient sex, or preoperative MRD1, between the recurrence and non-recurrence groups. The postoperative cylindrical diopter (adjusted odds ratio [OR] = 0.432, = 0.005), laterality (adjusted OR = 0.202, = 0.006), and preoperative MRD1 (adjusted OR = 0.617, = 0.019) were associated with ptosis recurrence after surgery. Differences between the recurrence and non-recurrence groups in spherical diopter and spherical equivalent (SE) before and after surgery were not statistically significant. In addition, preoperative refractive error and postoperative spherical diopter were not significantly associated with ptosis recurrence after correction surgery. : Ptosis recurrence after FMFS in pediatric cases of congenital ptosis is associated with refractive error. Timely refractive correction and amblyopia treatment may help to reduce ptosis recurrence.
先前关于矫正手术后上睑下垂复发的研究往往集中在术后并发症、手术方法和悬吊材料上，很少提及屈光不正。本研究旨在探讨儿童单纯性先天性上睑下垂矫正术后屈光不正与复发的潜在关系。
我们对 2017 年至 2020 年在中山眼科中心（ZOC）接受治疗的单纯性先天性上睑下垂患者的数据进行了回顾性分析。共纳入 85 例患者的 111 只眼，均接受额肌瓣悬吊术（FMFS）治疗单纯性先天性上睑下垂，无手术相关并发症。评估术后眼睑高度的变化。术前和随访期间（术后每 3 个月）评估睫状肌麻痹验光。术后复发定义为边缘反射距离 1（MRD1）<1mm。
在手术时的年龄、患者性别或术前 MRD1 方面，复发组和非复发组之间无统计学差异。术后圆柱镜度数（调整后优势比[OR] = 0.432， = 0.005）、偏侧性（调整后 OR = 0.202， = 0.006）和术前 MRD1（调整后 OR = 0.617， = 0.019）与术后上睑下垂复发相关。手术前后的球镜度数和等效球镜（SE）在复发组和非复发组之间无统计学差异。此外，术前屈光不正和术后球镜度数与矫正手术后上睑下垂复发无显著相关性。
FMFS 治疗儿童先天性上睑下垂后，上睑下垂复发与屈光不正有关。及时进行屈光矫正和弱视治疗可能有助于降低上睑下垂复发的风险。
