Gritskevich A A, Miroshkina I V, Piyanikin S S, Adyrkhayev Z A, Stepanova Yu A, Zotikov A E, Teplov A A, Kubyshkin V A, Revishvili A Sh
Vishnevsky Institute of Surgery Ministry of Health of the Russian Federation, Moscow, Russia.
Khirurgiia (Mosk). 2017(1):42-47. doi: 10.17116/hirurgia2017142-47.
To develop the method for extracorporeal partial nephrectomy under pharmaco-cold ischemia without ureter intersection with orthotopic replantation of renal vessels for RCC.
The study included 37 patients with morphologically confirmed RCC pT1a-Т3bN0M0-1G1-3 with intraparenchymal and central location of the tumor in cases of single kidney, comorbidity of contralateral kidney and kidney on the side of lesion.
Mean surgery time was 413.97±89.14 minutes. Mean time of warm ischemia was 8.39±4.75 minutes, cold ischemia - 151.41±41.29 minutes. Intraoperative and postoperative complications were detected in 3 (8.1%) and 18 (48.6%) patients respectively.
Extracorporeal partial nephrectomy under pharmaco-cold ischemia without ureter intersection with orthotopic replantation of renal vessels for RCC is a relatively safe organ-sparing treatment. It provides resection of large tumors with any location under prolonged cold ischemia without ureter intersection.
开发一种用于肾细胞癌的在药物性冷缺血下进行体外部分肾切除术且输尿管不交叉、肾血管原位再植的方法。
该研究纳入了37例经形态学确诊为肾细胞癌pT1a-Т3bN0M0-1G1-3的患者，肿瘤位于实质内或中央，为单肾、对侧肾合并病变侧肾的情况。
平均手术时间为413.97±89.14分钟。平均热缺血时间为8.39±4.75分钟，冷缺血时间为151.41±41.29分钟。分别有3例（8.1%）和18例（48.6%）患者出现术中及术后并发症。
对于肾细胞癌，在药物性冷缺血下进行体外部分肾切除术且输尿管不交叉、肾血管原位再植是一种相对安全的保留器官的治疗方法。它能在长时间冷缺血且输尿管不交叉的情况下切除任何位置的大肿瘤。
