人肾脏去甲肾上腺素的分泌。
Noradrenaline secretion by the human kidney.
作者信息
de Leeuw P W, Falke H E, Punt R, Birkenhäger W H
出版信息
Clin Sci Mol Med Suppl. 1978 Dec;4:85s-87s. doi: 10.1042/cs055085s.
PMID:282105
Abstract
- In 20 subjects with uncomplicated essential hypertension, 10 of whom were on propranolol treatment, several blood samples were drawn simultaneously from the renal artery and vein after angiographic studies. In these samples we determined concentrations of noradrenaline, active renin, aldosterone and cortisol. 2. Renal blood flow was measured in all patients by Hippuran-clearance and xenon-washout. 3. Despite marked variations in the arteriovenous difference of noradrenaline, it was apparent in both groups that the kidney is able to release noradrenaline. 4. In the propranolol-treated group noradrenaline secretion with untreated hypertensive patients.
摘要
- 在20例单纯原发性高血压患者中，其中10例正在接受普萘洛尔治疗，在血管造影研究后同时从肾动脉和静脉采集了几份血样。在这些样本中，我们测定了去甲肾上腺素、活性肾素、醛固酮和皮质醇的浓度。2. 所有患者均通过马尿酸清除率和氙洗脱法测量肾血流量。3. 尽管去甲肾上腺素的动静脉差异存在显著变化，但两组患者中肾脏能够释放去甲肾上腺素这一点是明显的。4. 在普萘洛尔治疗组中，去甲肾上腺素分泌情况与未治疗的高血压患者相同。 （注：原文最后一句表述似乎不完整，翻译时尽量按现有内容翻译）
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