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骨扫描检测到晚期乳腺癌患者发生双膦酸盐相关颌骨骨坏死：一例报告

Bisphosphonate-related osteonecrosis of jaws in advanced stage breast cancer was detected from bone scan: a case report.

作者信息

Chirappapha Prakasit, Kitudomrat Saowanee, Thongjood Thanaporn, Aroonroch Rangsima

机构信息

Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Dental Department, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Gland Surg. 2017 Feb;6(1):93-100. doi: 10.21037/gs.2016.07.04.

DOI:10.21037/gs.2016.07.04
PMID:28210558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5293650/
Abstract

Bisphosphonates (BPs) are indicated to treat skeletal-related events (SREs) for cancer patients with bone metastasis. We report a 79-year-old woman with advanced stage breast cancer with bone metastasis who was prescribed BPs (zoledronate), then developed osteonecrosis of jaw. We provide a brief review of the pathogenesis, diagnosis and treatment of this complication.

摘要

双膦酸盐类药物（BPs）被用于治疗骨转移癌患者的骨相关事件（SREs）。我们报告了一名79岁晚期乳腺癌伴骨转移的女性患者，她接受了BPs（唑来膦酸）治疗，随后发生了颌骨坏死。我们对该并发症的发病机制、诊断和治疗进行简要综述。

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本文引用的文献

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Bisphosphonate-related osteonecrosis of the jaws: Report of a case using conservative protocol.双膦酸盐相关颌骨骨坏死：采用保守方案的病例报告。
Spec Care Dentist. 2016 Jan;36(1):43-7. doi: 10.1111/scd.12143. Epub 2015 Nov 24.
2
Bisphosphonate Related Osteonecrosis of the Jaw: An Update.双膦酸盐相关颌骨坏死：最新进展
J Maxillofac Oral Surg. 2014 Dec;13(4):386-93. doi: 10.1007/s12663-013-0564-x. Epub 2013 Aug 9.
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Bisphosphonate-related osteonecrosis of the jaw: specificities.双膦酸盐相关颌骨坏死：特点
Oncol Rev. 2014 Sep 23;8(2):254. doi: 10.4081/oncol.2014.254.
4
RANK/RANKL/OPG signaling pathways in necrotic jaw bone from bisphosphonate-treated subjects.双膦酸盐治疗患者坏死颌骨中的RANK/RANKL/OPG信号通路
Eur J Histochem. 2015 Feb 3;59(1):2455. doi: 10.4081/ejh.2015.2455.
5
American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw--2014 update.美国口腔颌面外科医师协会关于药物相关性颌骨坏死的立场文件——2014年更新版
J Oral Maxillofac Surg. 2014 Oct;72(10):1938-56. doi: 10.1016/j.joms.2014.04.031. Epub 2014 May 5.
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Bisphosphonate-related osteonecrosis of the jaws: analysis of a case series at a dental school.双膦酸盐相关颌骨坏死：一所牙科学院的病例系列分析
Spec Care Dentist. 2014 Mar-Apr;34(2):77-83. doi: 10.1111/scd.12023.
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Platelet-rich plasma (PRP) in dental and oral surgery: from the wound healing to bone regeneration.富血小板血浆（PRP）在口腔和口腔颌面外科中的应用：从伤口愈合到骨再生。
Immun Ageing. 2013 Jun 13;10(1):23. doi: 10.1186/1742-4933-10-23.
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N Am J Med Sci. 2013 Apr;5(4):260-5. doi: 10.4103/1947-2714.110429.
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Stem Cells Dev. 2013 Jul 15;22(14):2047-56. doi: 10.1089/scd.2012.0615. Epub 2013 Apr 6.
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