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1
New developments for the detection and treatment of cardiac vasculopathy.心脏血管病变检测与治疗的新进展。
Curr Opin Cardiol. 2017 May;32(3):316-325. doi: 10.1097/HCO.0000000000000388.
2
European Association of Cardiovascular Imaging/Cardiovascular Imaging Department of the Brazilian Society of Cardiology recommendations for the use of cardiac imaging to assess and follow patients after heart transplantation.欧洲心血管影像协会/巴西心脏病学会心血管影像学部关于心脏移植后评估和随访患者使用心脏影像的建议。
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3
Diagnostic accuracy of dobutamine stress echocardiography in the detection of cardiac allograft vasculopathy in heart transplant recipients: A systematic review and meta-analysis study.多巴酚丁胺负荷超声心动图检测心脏移植受者心脏移植血管病变的诊断准确性:一项系统评价和荟萃分析研究
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4
[Quantitative dobutamine stress echocardiography in follow-up of heart transplantation: normal values and findings in patients with transplant vasculopathy].[定量多巴酚丁胺负荷超声心动图在心脏移植随访中的应用:正常值及移植血管病变患者的表现]
Z Kardiol. 1997 Oct;86(10):868-76. doi: 10.1007/s003920050126.
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Follow-up of heart transplant recipients with serial echocardiographic coronary flow reserve and dobutamine stress echocardiography to detect cardiac allograft vasculopathy.对心脏移植受者进行随访,采用连续超声心动图冠状动脉血流储备和多巴酚丁胺负荷超声心动图检测心脏移植血管病。
J Am Soc Echocardiogr. 2014 May;27(5):531-9. doi: 10.1016/j.echo.2014.01.020. Epub 2014 Mar 7.
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Cardiac Allograft Vasculopathy: Challenges and Advances in Invasive and Non-Invasive Diagnostic Modalities.心脏移植血管病变:有创和无创诊断方法的挑战与进展
J Cardiovasc Dev Dis. 2024 Mar 21;11(3):95. doi: 10.3390/jcdd11030095.
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Usefulness of dual imaging stress echocardiography for the diagnosis of coronary allograft vasculopathy in heart transplant recipients.双影像负荷超声心动图在诊断心脏移植受者冠状动脉移植血管病中的作用。
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Coronary computed tomography angiography for the detection of cardiac allograft vasculopathy: a meta-analysis of prospective trials.冠状动脉计算机断层扫描血管造影术检测心脏移植血管病:前瞻性试验的荟萃分析。
J Am Coll Cardiol. 2014 May 20;63(19):1992-2004. doi: 10.1016/j.jacc.2014.01.071. Epub 2014 Mar 26.
9
[Initial experiences with dobutamine stress echocardiography in heart transplant patients].
Z Kardiol. 1995 May;84(5):411-8.
10
Cardiac allograft vasculopathy: advances in diagnosis.心脏移植血管病:诊断进展。
Cardiol Rev. 2011 Jan-Feb;19(1):30-5. doi: 10.1097/CRD.0b013e3181fbde2f.

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Multiparametric Cardiac Magnetic Resonance Imaging Detects Altered Myocardial Tissue and Function in Heart Transplantation Recipients Monitored for Cardiac Allograft Vasculopathy.多参数心脏磁共振成像检测心脏移植受者心肌组织和功能的改变,这些受者接受了心脏移植血管病变的监测。
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TET2 Protects Against Vascular Smooth Muscle Cell Apoptosis and Intimal Thickening in Transplant Vasculopathy.TET2 可防止移植血管病中的血管平滑肌细胞凋亡和内膜增厚。
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Int J Cardiovasc Imaging. 2021 Apr;37(4):1461-1472. doi: 10.1007/s10554-020-02086-y. Epub 2020 Oct 29.
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Coronary revascularization after heart transplant - the search for prognostic factors.心脏移植后的冠状动脉血运重建——寻找预后因素。
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Semi-quantitative myocardial perfusion MRI in heart transplant recipients at rest: repeatability in healthy controls and assessment of cardiac allograft vasculopathy.静息状态下心脏移植受者的半定量心肌灌注 MRI:健康对照者的可重复性和心脏移植物血管病的评估。
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Progression of cardiac allograft vasculopathy assessed by serial three-vessel quantitative coronary angiography.采用连续三血管定量冠状动脉造影评估心脏移植血管病的进展。
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Lower frequency routine surveillance endomyocardial biopsies after heart transplantation.心脏移植后较低频率的常规监测心内膜心肌活检
PLoS One. 2017 Aug 25;12(8):e0182880. doi: 10.1371/journal.pone.0182880. eCollection 2017.

本文引用的文献

1
Donor-specific anti-HLA antibodies with antibody-mediated rejection and long-term outcomes following heart transplantation.心脏移植后具有抗体介导排斥反应的供体特异性抗HLA抗体及长期预后
J Heart Lung Transplant. 2017 May;36(5):540-545. doi: 10.1016/j.healun.2016.10.016. Epub 2016 Nov 17.
2
Impact of Statin Use After Heart Transplantation: A Meta-Analysis.心脏移植后使用他汀类药物的影响:一项荟萃分析。
Circ Heart Fail. 2016 Oct;9(10). doi: 10.1161/CIRCHEARTFAILURE.116.003265.
3
Dextran or Saline Can Replace Contrast for Intravascular Optical Coherence Tomography in Lower Extremity Arteries.右旋糖酐或生理盐水可替代造影剂用于下肢动脉血管内光学相干断层扫描
J Endovasc Ther. 2016 Oct;23(5):723-30. doi: 10.1177/1526602816657392. Epub 2016 Jul 5.
4
Dobutamine stress echocardiography is inadequate to detect early cardiac allograft vasculopathy.多巴酚丁胺负荷超声心动图不足以检测早期心脏移植血管病变。
J Heart Lung Transplant. 2016 Aug;35(8):1040-1. doi: 10.1016/j.healun.2016.05.012. Epub 2016 May 21.
5
Invasive Assessment of Coronary Physiology Predicts Late Mortality After Heart Transplantation.冠状动脉生理学的侵入性评估可预测心脏移植后的晚期死亡率。
Circulation. 2016 May 17;133(20):1945-50. doi: 10.1161/CIRCULATIONAHA.115.018741. Epub 2016 Apr 20.
6
The Registry of the International Society for Heart and Lung Transplantation: Thirty-second Official Adult Heart Transplantation Report--2015; Focus Theme: Early Graft Failure.国际心肺移植学会登记处:第三十二次成人心脏移植官方报告——2015年;重点主题:早期移植物功能衰竭
J Heart Lung Transplant. 2015 Oct;34(10):1244-54. doi: 10.1016/j.healun.2015.08.003. Epub 2015 Aug 28.
7
Optical coherence tomography for characterization of cardiac allograft vasculopathy in late survivors of pediatric heart transplantation.光学相干断层扫描用于儿童心脏移植后晚期幸存者心脏移植物血管病的特征描述。
J Heart Lung Transplant. 2016 Jan;35(1):74-79. doi: 10.1016/j.healun.2015.08.011. Epub 2015 Sep 3.
8
Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial.多支冠状动脉疾病患者经皮冠状动脉介入治疗中血流储备分数与血管造影指导的比较(FAME):一项随机对照试验的 5 年随访结果。
Lancet. 2015 Nov 7;386(10006):1853-60. doi: 10.1016/S0140-6736(15)00057-4. Epub 2015 Aug 30.
9
Interplay of coronary angiography and intravascular ultrasound in predicting long-term outcomes after heart transplantation.冠状动脉造影与血管内超声在预测心脏移植术后长期预后中的相互作用
J Heart Lung Transplant. 2015 Sep;34(9):1146-53. doi: 10.1016/j.healun.2015.01.990. Epub 2015 Feb 7.
10
Dobutamine stress echocardiography during follow-up surveillance in heart transplant patients: Diagnostic accuracy and predictors of outcomes.心脏移植患者随访监测期间的多巴酚丁胺负荷超声心动图:诊断准确性及预后预测因素
J Heart Lung Transplant. 2015 May;34(5):710-7. doi: 10.1016/j.healun.2014.11.019. Epub 2014 Nov 17.

心脏血管病变检测与治疗的新进展。

New developments for the detection and treatment of cardiac vasculopathy.

作者信息

Clerkin Kevin J, Ali Ziad A, Mancini Donna M

机构信息

aDepartment of Medicine, Division of Cardiology, Columbia University Medical Center bCardiovascular Research Foundation cDepartment of Medicine, Division of Cardiology, Icahn School of Medicine at Mount Sinai, New York, USA.

出版信息

Curr Opin Cardiol. 2017 May;32(3):316-325. doi: 10.1097/HCO.0000000000000388.

DOI:10.1097/HCO.0000000000000388
PMID:28212149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5654693/
Abstract

PURPOSE OF REVIEW

Cardiac allograft vasculopathy (CAV) is a major limitation to long-term survival after heart transplantation. Innovative new techniques to diagnose CAV have been applied to detect disease. This review will examine the current diagnostic and treatment options available to clinicians for CAV.

RECENT FINDINGS

Diagnostic modalities addressing the pathophysiology underlying CAV (arterial wall thickening and decreased coronary blood flow) improve diagnostic sensitivity when compared to traditional (angiography and dobutamine stress echocardiography) techniques.

SUMMARY

Limited options are available to prevent and treat CAV; however, progress has been made in making an earlier and more accurate diagnosis. Future research is needed to identify the optimal time to modify immunosuppression and investigate novel treatments for CAV.

摘要

综述目的

心脏移植术后同种异体移植物血管病变(CAV)是长期生存的主要限制因素。已应用创新新技术来诊断CAV以检测疾病。本综述将探讨临床医生目前可用于CAV的诊断和治疗选择。

最新发现

与传统(血管造影和多巴酚丁胺负荷超声心动图)技术相比,针对CAV潜在病理生理学(动脉壁增厚和冠状动脉血流减少)的诊断方法可提高诊断敏感性。

总结

预防和治疗CAV的选择有限;然而,在更早、更准确的诊断方面已取得进展。需要未来的研究来确定调整免疫抑制的最佳时机,并研究CAV的新治疗方法。