García-Gallegos Diego Jesús, Luis-López Eliseo
Unidad de Cuidados Intensivos, Centro Médico Nacional del Bajío, Instituto Mexicano del Seguro Social, León, Guanajuato, México.
Rev Med Inst Mex Seguro Soc. 2017;55 Suppl 1:S14-S19.
It is not known if patients with prediabetes, a subgroup of non-diabetic patients that usually present hyperinsulinemia, have higher risk to present stress-induced hyperglycemia. The objective was to determine if prediabetes is a risk marker to present stress-induced hyperglycemia.
Analytic, observational, prospective cohort study of non-diabetic critically ill patients of a third level hospital. We determined plasmatic glucose and glycated hemoglobin (HbA1c) at admission to diagnose stress-induced hyperglycemia (glucose ≥ 140 mg/dL) and prediabetes (HbA1c between 5.7 and 6.4%), respectively. We examined the proportion of non-prediabetic and prediabetic patients that developed stress hyperglycemia with contingence tables and Fisher's exact test for nominal scales.
Of 73 patients studied, we found a proportion of stress-induced hyperglycemia in 6.6% in those without prediabetes and 61.1% in those with prediabetes. The Fisher's exact test value was 22.46 (p < 0.05).
Prediabetes is a risk marker for stress-induced hyperglycemia in critically ill adults.
