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儿童心脏骤停复苏后医院感染的发生率及预后

Incidence and prognosis of nosocomial infection after recovering of cardiac arrest in children.

作者信息

Fernández Andrés, Solís Ana, Cañete Paloma, Del Castillo Jimena, Urbano Javier, Carrillo Angel, López-Herce Jesús

机构信息

Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón de Madrid, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón Facultad de Medicina, Universidad Complutense de Madrid, Spain.

Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón de Madrid, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón Facultad de Medicina, Universidad Complutense de Madrid, Spain.

出版信息

Resuscitation. 2017 Apr;113:87-89. doi: 10.1016/j.resuscitation.2017.02.002. Epub 2017 Feb 16.

Abstract

OBJECTIVE

to analyze the incidence of infection in children who have suffered an in-hospital cardiac arrest (CA) and the association with mortality.

METHODS

A retrospective unicenter observational study on a prospective database with children between one month and 16 years old, who have suffered an in-hospital CA was performed. Clinical, analytical and monitorization data, treatment, mortality and cause of death were recorded.

RESULTS

57 children were studied (57.6% males). Recovery of spontaneous circulation (ROSC) was achieved in 50 children (87.7%) and 32 (59.3%) survived. After ROSC, 28 patients (56% of those who achieved ROSC) were diagnosed of infection. There were not significant differences in mortality between patients infected (42.9%) and uninfected (27.3%) p=0.374. Only one died in consequence of a sepsis with multiorganic failure.

CONCLUSIONS

The frequency of infection in children after recovering of a cardiac arrest is high. There were no statistically significant differences in mortality between patients with and without infection after ROSC.

摘要

目的

分析院内发生心脏骤停(CA)患儿的感染发生率及其与死亡率的关联。

方法

对一个前瞻性数据库进行回顾性单中心观察性研究,该数据库纳入了年龄在1个月至16岁之间、院内发生CA的患儿。记录临床、分析及监测数据、治疗情况、死亡率及死亡原因。

结果

共研究了57例患儿(男性占57.6%)。50例患儿(87.7%)实现自主循环恢复(ROSC),32例(59.3%)存活。ROSC后,28例患者(占实现ROSC患者的56%)被诊断为感染。感染患者(42.9%)与未感染患者(27.3%)的死亡率无显著差异(p = 0.374)。仅1例因脓毒症伴多器官功能衰竭死亡。

结论

心脏骤停复苏后患儿的感染发生率较高。ROSC后感染患者与未感染患者的死亡率无统计学显著差异。

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