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用于一次性一维映射的低场单侧核磁共振:在膜中的应用。

Low-field single-sided NMR for one-shot 1D-mapping: Application to membranes.

作者信息

Judeinstein Patrick, Ferdeghini Filippo, Oliveira-Silva Rodrigo, Zanotti Jean-Marc, Sakellariou Dimitrios

机构信息

Laboratoire Léon Brillouin, CNRS-CEA (UMR 12), CNRS, Université Paris-Saclay, CEA Saclay, 91191 Gif-sur-Yvette Cedex, France; Laboratoire de Physique des Solides, (UMR CNRS 8502), Univ. Paris-Sud, Université Paris-Saclay, 91405 Orsay, France.

Laboratoire Léon Brillouin, CNRS-CEA (UMR 12), CNRS, Université Paris-Saclay, CEA Saclay, 91191 Gif-sur-Yvette Cedex, France.

出版信息

J Magn Reson. 2017 Apr;277:25-29. doi: 10.1016/j.jmr.2017.02.003. Epub 2017 Feb 8.

Abstract

Many single-sided permanent magnet NMR systems have been proposed over the years allowing for 1D proton-density profiling, diffusion measurements and relaxometry. In this manuscript we make use of a recently published unilateral magnet for low-field NMR exhibiting an extremely uniform magnetic field gradient with moderate strength and cylindrical symmetry, allowing for a well-defined sweet spot. Combined with a goniometer, our system is used to characterize precisely the uniformity of its gradient and to achieve micrometric precision 1D profiling, as well as spatially localized relaxometry and diffusometry on thick (∼150μm) membrane samples. Profiling with this magnet did not require repositioning of the samples with respect to the 1D tomograph.

摘要

多年来,人们提出了许多单边永磁核磁共振系统,可用于一维质子密度分析、扩散测量和弛豫测量。在本论文中,我们使用了一种最近发表的用于低场核磁共振的单边磁体,该磁体具有中等强度且呈圆柱对称的极其均匀的磁场梯度,从而形成了一个明确的最佳检测点。结合测角仪,我们的系统用于精确表征其梯度的均匀性,并在厚(约150μm)膜样品上实现微米级精度的一维分析,以及空间定位弛豫测量和扩散测量。使用这种磁体进行分析时,无需相对于一维断层扫描仪重新定位样品。

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