Arlen Angela M
Department of Urology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 3RCP, Iowa City, IA, 52242-1089, USA.
Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Curr Urol Rep. 2017 Feb;18(2):14. doi: 10.1007/s11934-017-0656-0.
Dysfunctional voiding is defined as "habitual contraction of the urethral sphincter during voiding." Children with dysfunctional voiding remain a challenge, and the approach to and management of LUT dysfunction varies widely among programs and providers with the role of pharmacotherapy being ill defined.
Animated biofeedback is the current treatment modality of choice in children who are not responsive to standard urotherapy. Comprehensive biofeedback programs incorporate continued elimination education, voiding diaries, and home exercises with high success rates. Recent studies suggest botulinum toxin A results in persistent satisfactory results in select children with refractory dysfunctional voiding. Conservative measures including an aggressive bowel regimen and timed voiding are the mainstays of treatment, and motivated children with persistent symptoms often respond favorably to escalating urotherapy with biofeedback. Pharmacotherapy plays an ancillary role in the management of dysfunctional voiding.
功能性排尿障碍被定义为“排尿时尿道括约肌习惯性收缩”。患有功能性排尿障碍的儿童仍然是一个挑战,不同的项目和医疗服务提供者对下尿路功能障碍的处理方法和管理差异很大,药物治疗的作用也不明确。
动画生物反馈是对标准尿疗法无反应的儿童当前首选的治疗方式。全面的生物反馈项目包括持续的排尿教育、排尿日记和家庭锻炼,成功率很高。最近的研究表明,肉毒杆菌毒素A在某些难治性功能性排尿障碍儿童中能产生持续满意的效果。保守措施包括积极的肠道管理方案和定时排尿是治疗的主要方法,有积极性且有持续症状的儿童通常对加强尿疗法和生物反馈治疗反应良好。药物治疗在功能性排尿障碍的管理中起辅助作用。