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[向新妈妈主动提供麻疹、风疹和腮腺炎疫苗:意大利拉齐奥大区罗马市一个地方卫生单位的医疗机构经验]

[The active offering of measles, rubella and mumps vaccine in new mothers: the experience of health facilities in one of the Local Health Unit of Rome, Lazio, Italy].

作者信息

Santoro Viviana, Pettinicchio Valentina, Lancia Andreina, Vazzoler Cristiana, De Luca Francesca, Franco Elisabetta

机构信息

Scuola di Specializzazione in Igiene e Medicina Preventiva, Università degli Studi di Roma "Tor Vergata", Roma, Italia.

Distretto Sanitario 12 ex ASL RMC, Roma, Italia.

出版信息

Ig Sanita Pubbl. 2016 Nov-Dec;72(6):589-597.

Abstract

Rubella is a contagious disease that can be very serious, especially in unvaccinated pregnant women. The best way to be protected is getting vaccinated: MMR vaccine is very effective at protecting people against measles, mumps, and rubella, and preventing the complications caused by these diseases. According to PASSI 2012-2015 (the Italian behavioral risk factor surveillance system) in the territory of ex ASL Roma C only 56% of women between 18 and 49 years were immunized against rubella, thanks to vaccination (34%) or past infection detected by rubeotest (22%); 2% was susceptible and 42% of respondents did not know their immune status against rubella. The Italian National Plan for the Elimination of Measles and Congenital Rubella (PNEMoRc) 2010-15 had the aim to reduce the prevalence of rubella susceptibility in young women (<5%), to reduce the prevalence of congenital rubella and to increase MMR vaccination coverage. This plan suggested to promote actions to spread correct information about MMR vaccine in the general population and healthcare workers and to offer this vaccine to susceptible women during every appropriate contact with the Family planning clinics. In order to ensure and monitor these recommendations, a recovery procedure for MMR vaccine was activated in 2015 for women who contacted the health facilities for their first child vaccination. A form was developed in order to collect information about women's immune status against rubella and measles. According to this tool all women who stated they had never been vaccinated for rubella or MMR and/or did not remember vaccination and/or had never had a rubeotest were considered susceptible to rubella. Women susceptible to rubella were invited to undergo vaccination. Data collected during one year activity were recorded and analyzed with Epinfo 7.0 software. We collected 1801 correctly filled forms; 88.6% (1595) of women were evaluated immune to rubella and 11.4% susceptible. The prevalence of susceptibility seems to be influenced by age, from 16% in the youngest age group to 9% in the >35 years. Among 206 women susceptible to rubella: 38% were vaccinated, 31% preferred to wait, 11% refused vaccination and for 20% data is missing. The protocol of MMR vaccine recovery was effective, and allowed to reach a good number of women who had a contact with the health facilities and we hope this number to be bigger, adding a part of those women who preferred to wait. However, data of a year activity indicate that vaccine recovery initiatives should be proposed and implemented, in consideration of the proportion of rubella susceptibility in women who were recently pregnant.

摘要

风疹是一种传染性疾病,可能非常严重,尤其是在未接种疫苗的孕妇中。预防风疹的最佳方法是接种疫苗:麻腮风疫苗(MMR)在预防麻疹、腮腺炎和风疹以及预防这些疾病引起的并发症方面非常有效。根据2012 - 2015年意大利行为风险因素监测系统(PASSI)的数据,在原罗马C区卫生局辖区内,18至49岁的女性中,只有56%接种了风疹疫苗,其中通过接种疫苗(34%)或风疹检测(rubeotest)检测出既往感染(22%);2%为易感人群,42%的受访者不知道自己对风疹的免疫状态。2010 - 2015年意大利消除麻疹和先天性风疹国家计划(PNEMoRc)的目标是降低年轻女性中风疹易感性的患病率(<5%),降低先天性风疹的患病率,并提高MMR疫苗接种覆盖率。该计划建议采取行动,向普通人群和医护人员传播有关MMR疫苗的正确信息,并在与计划生育诊所的每次适当接触中为易感女性提供这种疫苗。为了确保并监测这些建议,2015年针对首次联系医疗机构为其第一个孩子接种疫苗的女性启动了MMR疫苗补种程序。设计了一份表格,以收集有关女性风疹和麻疹免疫状态的信息。根据该工具,所有表示从未接种过风疹疫苗或MMR疫苗和/或不记得接种情况和/或从未进行过风疹检测的女性都被视为风疹易感人群。邀请风疹易感女性接种疫苗。使用Epinfo 7.0软件记录和分析一年活动期间收集的数据。我们收集了1801份填写正确的表格;88.6%(1595名)女性被评估为对风疹免疫,11.4%为易感人群。易感性患病率似乎受年龄影响,最年轻年龄组为16%,>35岁年龄组为9%。在206名风疹易感女性中:38%接种了疫苗,31%选择等待,11%拒绝接种,20%的数据缺失。MMR疫苗补种程序是有效的,能够接触到大量与医疗机构有接触的女性,我们希望这个数字能够更大,将一部分选择等待的女性也包括进来。然而,一年活动的数据表明,考虑到近期怀孕女性中风疹易感性的比例,应提出并实施疫苗补种倡议。

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