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腹腔镜下人工尿道括约肌植入术治疗女性固有括约肌功能不全的中期疗效

Laparoscopic implantation of artificial urinary sphincter in women with intrinsic sphincter deficiency: Mid-term outcomes.

作者信息

Ferreira Carlos, Brychaert Pierre-Emannuel, Menard Johann, Mandron Eric

机构信息

Department of Urology, Surgical Clinic Du Pré, Technopôle Université, Le Mans, France.

出版信息

Int J Urol. 2017 Apr;24(4):308-313. doi: 10.1111/iju.13296. Epub 2017 Feb 19.

Abstract

OBJECTIVES

To analyze the safety and the mid-term continence rates of laparoscopic implantation of artificial urinary sphincter in women.

METHODS

A total of 52 women with intrinsic sphincter deficiency underwent a laparoscopic artificial urinary sphincter implantation from 2005 to 2015 at Surgical Clinic Du Pré, Le Mans, France. The artificial urinary sphincter was implanted around the bladder neck by a transperitoneal laparoscopic approach to the Retzius space. Urodynamic assessment was carried out. Postoperative functional outcome was defined as success (no leaking, no pad use), improvement (>50% decrease in number of leakages, >50% decrease in number of pads used or use of light protection) or failure (<50% improvement, persistent or increased leaking). Outcome measures also included perioperative and long-term complications.

RESULTS

The mean age of the patients was 69.1 years (range 64-82 years). After a mean follow up of 37.5 months (median 24 months; range 1-125 months), 38 (77.6%) patients were considered to be continent (no leakage, no pads), and eight (16.3%) improved their grade of incontinence. Three patients abandoned the follow-up schedule and were excluded. There was no perioperative severe complication. Artificial urinary sphincter revision was needed in 11 (22.4%) patients, requiring a total of seven redo procedures and four permanent sphincter removals. The main reasons for redo procedures were six (11.2%) mechanical problems and one vaginal erosion (2%).

CONCLUSIONS

Herein we report one of the largest series with the longest follow up evaluating the outcomes of laparoscopic artificial urinary sphincter implantation in female patients. This approach seems to be a safe and effective treatment option for patients with intrinsic sphincter deficiency.

摘要

目的

分析女性腹腔镜植入人工尿道括约肌的安全性及中期控尿率。

方法

2005年至2015年期间,共有52例患有内在括约肌缺陷的女性在法国勒芒市迪普雷外科诊所接受了腹腔镜人工尿道括约肌植入手术。通过经腹腹腔镜入路至Retzius间隙,将人工尿道括约肌植入膀胱颈周围。进行了尿动力学评估。术后功能结局定义为成功(无漏尿、无需使用尿垫)、改善(漏尿次数减少>50%、尿垫使用次数减少>50%或使用轻度防护用品)或失败(改善<50%、持续漏尿或漏尿增加)。结局指标还包括围手术期和长期并发症。

结果

患者的平均年龄为69.1岁(范围64 - 82岁)。平均随访37.5个月(中位数24个月;范围1 - 125个月)后,38例(77.6%)患者被认为控尿良好(无漏尿、无需尿垫),8例(16.3%)患者的尿失禁等级有所改善。3例患者放弃随访计划并被排除。无围手术期严重并发症。11例(22.4%)患者需要进行人工尿道括约肌翻修,共需要7次再次手术和4次永久性括约肌移除。再次手术的主要原因是6例(共11.2%)机械问题和1例(共2%)阴道侵蚀。

结论

本文报告了评估女性患者腹腔镜人工尿道括约肌植入结局的最大系列研究之一,且随访时间最长。对于内在括约肌缺陷患者,这种方法似乎是一种安全有效的治疗选择。

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