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过去50年人工尿道括约肌与女性压力性尿失禁:一项叙述性综述

Artificial urinary sphincter and female stress urinary incontinence over the past 50 years: a narrative review.

作者信息

Madanelo Mariana, Chartier-Kastler Emmanuel, Greenwell Tamsin, Gray Gary, Khavari Rose, Van Koeveringe Gommert A, Van Der Aa Frank, Peyronnet Benoit

机构信息

Department of Urology, Centro Hospitalar Universitário de Santo António, Porto, Portugal.

Department of Urology, Pitié-Salpêtrière University Hospital, Paris Sorbonne University, Paris, France.

出版信息

Transl Androl Urol. 2024 Aug 31;13(8):1674-1686. doi: 10.21037/tau-23-58. Epub 2023 Nov 8.

Abstract

BACKGROUND AND OBJECTIVE

The aim of the present report was to provide an overview of the use of the artificial urinary sphincter (AUS) in adult females with stress urinary incontinence (SUI) over the past 50 years.

METHODS

A literature search was conducted in December 2022 and January 2023 using the MEDLINE and Embase databases, screening for randomized controlled trials (RCTs), prospective and retrospective series and reviews on AUS. Only articles published in English or French were included. The search strategy involved a free text protocol and the narrative review reporting checklist was completed.

KEY CONTENT AND FINDINGS

The AUS is a device used over the past 50 years for SUI caused by intrinsic sphincter deficiency (ISD). It has the theoretical ability to simulate the function of a biological urinary sphincter. Although the role of the AUS for females with ISD remains heterogeneous from one part of the world to the other, the existing literature demonstrates that AUS yields satisfactory functional outcomes in female SUI patients, comparable or better to what has been reported in male AUS series. Hence, the main barrier to its adoption has so far been the technical challenge of its implantation at the bladder neck. Regarding the results of AUS implantation in females, we included in this review 3 reviews, retrospective studies and 1 prospective study. In recent years, robotic techniques of female AUS implantation have spread significantly with promising outcomes including numerous reports suggesting that it may decrease its morbidity. In the near future, the development of electromechanical devices may further expand the role of AUS in the management of female SUI.

CONCLUSIONS

While the use of AUS in female patients provides excellent functional outcomes, it has been limited to scarce centers. However, due to the rise of minimally invasive approaches, it has started spreading again over the past few years. The future of AUS is likely to be bright, fed by technological advances of the device and robotic surgical system, high level of evidence studies and joint efforts of the urological community to facilitate its diffusion across the world.

摘要

背景与目的

本报告旨在概述过去50年人工尿道括约肌(AUS)在成年女性压力性尿失禁(SUI)中的应用情况。

方法

于2022年12月和2023年1月使用MEDLINE和Embase数据库进行文献检索,筛选关于AUS的随机对照试验(RCT)、前瞻性和回顾性系列研究以及综述。仅纳入以英文或法文发表的文章。检索策略采用自由文本协议,并完成叙述性综述报告清单。

关键内容与发现

AUS是过去50年用于治疗由内在括约肌缺陷(ISD)引起的SUI的一种装置。它具有模拟生物尿道括约肌功能的理论能力。尽管在世界不同地区,AUS对患有ISD的女性的作用仍存在差异,但现有文献表明,AUS在女性SUI患者中产生了令人满意的功能结果,与男性AUS系列报道的结果相当或更好。因此,迄今为止其应用的主要障碍是在膀胱颈植入的技术挑战。关于女性AUS植入的结果,本综述纳入了3篇综述、回顾性研究和1篇前瞻性研究。近年来,女性AUS植入的机器人技术已显著推广,取得了令人鼓舞的结果,包括大量报告表明它可能降低其发病率。在不久的将来,机电装置的发展可能会进一步扩大AUS在女性SUI管理中的作用。

结论

虽然AUS在女性患者中的应用提供了出色的功能结果,但仅限于少数中心。然而,由于微创方法的兴起,在过去几年中它又开始再次普及。AUS的未来可能是光明的,这得益于该装置和机器人手术系统的技术进步、高水平的循证研究以及泌尿外科界为促进其在全球传播所做的共同努力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac3/11399035/ed2f8e362ec7/tau-13-08-1674-f1.jpg

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