Røsok Bård I, de Rooij Thijs, van Hilst Jony, Diener Markus K, Allen Peter J, Vollmer Charles M, Kooby David A, Shrikhande Shailesh V
Section for HPB Surgery, Department of Gastrointestinal Surgery, Oslo University Hospital, Oslo, Norway.
Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.
HPB (Oxford). 2017 Mar;19(3):205-214. doi: 10.1016/j.hpb.2017.01.009. Epub 2017 Feb 16.
The first International conference on Minimally Invasive Pancreas Resection was arranged in conjunction with the annual meeting of the International Hepato-Pancreato-Biliary Association (IHPBA), in Sao Paulo, Brazil on April 19th 2016. The presented evidence and outcomes resulting from the session for minimally invasive distal pancreatectomy (MIDP) is summarized and addressed perioperative outcome, the outcome for cancer and patient selection for the procedure.
A literature search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to compare MIDP and open distal pancreatectomy. Patient selection was discussed based on plenary talks, panel discussions and a worldwide survey on MIDP.
Of 582 studies, 52 (40 observational and 12 case-matched) were included in the assessment for outcome for LDP (n = 5023) vs. ODP (n = 16,306) whereas 16 observational comparative studies were identified for cancer outcome. No randomized trials were identified. MIDP resulted in similar outcome to ODP with a tendency for lower blood loss and shorter hospital stay in the MIDP group.
Available evidence for comparison of MIDP to ODP is weak, although the number of studies is high. Observed outcomes of MIDP are promising. In the absence of randomized control trials, an international registry should be established.
2016年4月19日,首届微创胰腺切除术国际会议与国际肝胆胰协会(IHPBA)年会在巴西圣保罗联合召开。会议总结了微创远端胰腺切除术(MIDP)的相关证据和结果,并探讨了围手术期结果、癌症治疗结果以及该手术的患者选择。
根据系统评价和Meta分析的首选报告项目(PRISMA)指南进行文献检索,以比较MIDP和开放性远端胰腺切除术。基于全会报告、小组讨论以及一项关于MIDP的全球调查,对患者选择进行了讨论。
在582项研究中,52项(40项观察性研究和12项病例匹配研究)被纳入评估LDP(n = 5023)与ODP(n = 16306)的结果,而关于癌症结果的观察性比较研究有16项。未发现随机对照试验。MIDP的结果与ODP相似,MIDP组有失血较少和住院时间较短的趋势。
尽管研究数量众多,但比较MIDP与ODP的现有证据薄弱。MIDP的观察结果很有前景。在缺乏随机对照试验的情况下,应建立一个国际注册机构。