[Changes in the microviscosity of the plasma membrane and sensitivity to PGE1 of platelets stored at 22 and 4 degrees C].

Effect of platelet storage within 1-3 days on the cell membranes microviscosity, studied by means of a spin probe, and their sensitivity to PGEI, inhibitor of ADP aggregation, were studied. The highest values of fluidity and PGEI sensitivity exhibited plasmatic membranes of platelets stored at 22 degrees; lower values were found in the membranes stored at 4 degrees as compared with native fresh platelets. The data obtained suggest the dissimilar character of alterations in structure and functions of platelet plasmatic membrane during storage at 22 degrees and 4 degrees.