Aoyama Ken-Ichi, Otsuru Mitsunobu, Uchibori Masahiro, Ota Yoshihide
Division of Oral and Maxillofacial Surgery, School of Medicine, Tokai University, Tokyo, Japan; Division of Oral and Maxillofacial Surgery, Oiso Hospital, Japan.
Division of Oral and Maxillofacial Surgery, School of Medicine, Tokai University, Tokyo, Japan.
World J Nucl Med. 2017 Jan-Mar;16(1):68-70. doi: 10.4103/1450-1147.174712.
Kikuchi-Fujimoto disease (KFD) is a benign but self-limiting disorder. However, KFD is often misdiagnosed as a malignant disease. Although 18F-fludeoxyglucose (FDG) uptake on dual-time-point imaging (DTPI) positron emission tomography (PET)/computed tomography (CT) is useful in distinguishing malignant from benign disease, the latter sometimes mimics malignancy on DTPI PET/CT, resulting in a misdiagnosis. Here, we describe the case of a 30-year-old woman who complained of cervical lymphadenopathy. PET showed increased FDG uptake in multiple lymph nodes, with a maximum standardized uptake value (SUVmax) of 19.0 in the early phase to 21.8 in the late phase. A biopsy was performed, and pathological examination revealed KFD. KFD with FDG uptake in lymph nodes on DTPI PET/CT is rare and difficult to be distinguished from a malignant disease.
菊池-藤本病（KFD）是一种良性但自限性的疾病。然而，KFD常被误诊为恶性疾病。尽管双时相成像（DTPI）正电子发射断层扫描（PET）/计算机断层扫描（CT）上的18F-氟脱氧葡萄糖（FDG）摄取有助于区分恶性和良性疾病，但后者在DTPI PET/CT上有时会表现出类似恶性肿瘤的特征，从而导致误诊。在此，我们描述了一名30岁女性主诉颈部淋巴结病的病例。PET显示多个淋巴结FDG摄取增加，早期最大标准化摄取值（SUVmax）为19.0，晚期为21.8。进行了活检，病理检查显示为KFD。DTPI PET/CT上淋巴结有FDG摄取的KFD很罕见，且难以与恶性疾病区分开来。
