Olagunju Andrew Toyin, Adegbaju Dapo Adebowale, Uwakwe Richard
Department of Psychiatry, College of Medicine, University of Lagos , Nigeria.
Federal Neuropsychiatric Hospital , Yaba, Lagos, Nigeria.
Ment Illn. 2016 Dec 21;8(2):6647. doi: 10.4081/mi.2016.6647. eCollection 2016 Nov 23.
Evidence-based rehabilitative treatment is constrained due to limited knowledge about disability and its related factors among individuals with schizophrenia across West Africa. This study aims to investigate the pattern of disability, and the associated factors among individuals with schizophrenia. One hundred consecutively recruited consenting participants were subjected to designed questionnaire to inquire about their demographic and illness-related variables. This was followed by the administration of Structured Clinical Interview for DSM-IV-TR Axis I Disorders and Brief Psychiatric Rating Scale to confirm the diagnosis of schizophrenia and rate severity of symptoms respectively in them. In addition, the World Health Organisation Disability Assessment Scale II (WHODAS-II) was used to assess for disability in all participants. Different degrees of disability based on WHODAS-II mean score of 27.02±3.49 were noted among individuals with schizophrenia, and affectation of domains of disability like self care, getting along with others, life activities and participation in the society among others were observed. In addition, high level of disability was significantly associated with younger adults in the age group 18-44 years (P=0.007), unemployment status (P=0.003), remittance source of income (P=0.034) and ethnicity (P=0.017); conversely, less number of children (P=0.033), less amount spent on treatment (P<0.001) and lower BPRS score (P<0.001) correlated negatively with high level of disability. In spite of clinical stability following treatment, individuals with schizophrenia were disabled to varied degrees, and socioeconomic as well as illness-related factors constituted important correlates. Integration of rehabilitation along with social intervention into treatment design to reduce disability is implied, and further research is also warranted.
由于西非精神分裂症患者对残疾及其相关因素的了解有限,循证康复治疗受到限制。本研究旨在调查精神分裂症患者的残疾模式及其相关因素。连续招募了100名同意参与的参与者,让他们填写设计好的问卷,询问其人口统计学和疾病相关变量。随后,使用《精神障碍诊断与统计手册》第四版轴I障碍的结构化临床访谈和简明精神病评定量表分别确认精神分裂症的诊断并评估症状严重程度。此外,使用世界卫生组织残疾评定量表第二版(WHODAS-II)对所有参与者进行残疾评估。精神分裂症患者中,根据WHODAS-II平均得分27.02±3.49发现了不同程度的残疾,并观察到残疾领域受到影响,如自我护理、与他人相处、生活活动和社会参与等。此外,高水平残疾与18-44岁的年轻人(P=0.007)、失业状况(P=0.003)、汇款收入来源(P=0.034)和种族(P=0.017)显著相关;相反,子女数量较少(P=0.033)、治疗费用较低(P<0.001)和较低的BPRS得分(P<0.001)与高水平残疾呈负相关。尽管治疗后临床症状稳定,但精神分裂症患者仍存在不同程度的残疾,社会经济以及疾病相关因素是重要的相关因素。这意味着在治疗设计中应将康复与社会干预相结合以减少残疾,并且还需要进一步的研究。