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一种罕见的真菌感染:由[具体真菌名称未给出]引起的暗色丝孢霉病及文献综述

A rare fungal infection: Phaehyphomycosis due to and review of literature.

作者信息

Welfringer Anne, Vuong Valérie, Argy Nicolas, Chochillon Christian, Deschamps Lydia, Rollin Guillaume, Harent Stanislas, Joly Véronique, Vindrios William, Descamps Vincent

机构信息

Department of dermatology, Hospital Bichat, University Paris Diderot, Paris, France.

Department of Parasitology-mycology, Hospital Bichat, University Paris Descartes, Paris, France.

出版信息

Med Mycol Case Rep. 2017 Feb 5;15:21-24. doi: 10.1016/j.mmcr.2017.02.001. eCollection 2017 Mar.

DOI:10.1016/j.mmcr.2017.02.001
PMID:28217435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5300299/
Abstract

We report a rare case of phaehyphomycosis in a 71-year-old heart transplant recipient Togo native patient. Four months after the transplant, he presented painless nodules on the right heel with superficial ulceration. The polyphasic identification uncovered a rare cause of phaehyphomycose: V. botryosa. The treatment combined surgical excision of the lesions and anti-fungal therapy with posaconazole. We discussed eleven reported cases in literature since 1990.

摘要

我们报告了一例罕见的暗色丝孢霉病,患者为一名71岁的心脏移植受者,是来自多哥的本地人。移植后四个月,他的右脚跟出现无痛性结节并伴有浅表溃疡。多相鉴定发现了一种罕见的暗色丝孢霉病病因:葡萄穗霉。治疗方法包括手术切除病灶以及使用泊沙康唑进行抗真菌治疗。我们讨论了自1990年以来文献报道的11例病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1744/5300299/9612dd685c2a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1744/5300299/24958f1c8146/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1744/5300299/9612dd685c2a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1744/5300299/24958f1c8146/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1744/5300299/9612dd685c2a/gr2.jpg

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本文引用的文献

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Severe disseminated phaeohyphomycosis in an immunocompetent patient caused by Veronaea botryosa. Veronaea botryosa 引起免疫功能正常患者严重播散性暗色丝孢霉病。
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Mycopathologia. 2013 Jun;175(5-6):505-13. doi: 10.1007/s11046-013-9631-6. Epub 2013 Mar 6.
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Molecular phylogeny and proposal of two new species of the emerging pathogenic fungus Saksenaea.
采用非培养方法对人类疾病的黑酵母样病原体进行环境勘探。
Sci Rep. 2020 Aug 26;10(1):14229. doi: 10.1038/s41598-020-70915-0.
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Experimental Infection of Mice with as a Model for Human Phaeohyphomycosis.以小鼠实验性感染作为人类暗色丝孢霉病的模型
Comp Med. 2019 Aug 1;69(4):270-275. doi: 10.30802/AALAS-CM-18-000151. Epub 2019 Aug 6.
分子系统发育及新兴致病真菌沙壳菌属两个新种的提出。
J Clin Microbiol. 2010 Dec;48(12):4410-6. doi: 10.1128/JCM.01646-10. Epub 2010 Oct 6.
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A rare complication of ear piercing: a case of subcutaneous phaeohyphomycosis caused by Veronaea botryosa in China.耳部穿孔的罕见并发症:中国一株堇壳孢引起的皮下外瓶霉病。
Med Mycol. 2011 Apr;49(3):296-302. doi: 10.3109/13693786.2010.513340. Epub 2010 Sep 21.
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Cutaneous phaeohyphomycosis caused by Veronaea botryosa observed as sclerotic cells in tissue.
Int J Dermatol. 2007 Jun;46(6):625-7. doi: 10.1111/j.1365-4632.2007.02950.x.
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Cutaneous phaeohyphomycosis caused by an Itraconazole and Amphoterecin B resistant strain of Veronaeae botryosa.由对伊曲康唑和两性霉素B耐药的葡萄穗霉属菌株引起的皮肤暗色丝孢霉病。
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