Tahririan Mohammad Ali, Moezi Mehdi, Motififard Mahdi, Nemati Mahdi, Nemati Amin
Department of Orthopedic, Kashani Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Physical Medicine and Rehabilitation, Hafez Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Adv Biomed Res. 2016 Dec 27;5:200. doi: 10.4103/2277-9175.190939. eCollection 2016.
Degenerative changes and inflammation in the rotator cuff (RC) are the most important causes of shoulder pain. The aim of the present study was to determine the effectiveness of platelet-rich plasma (PRP) in patients with chronic RC tendinopathy.
This study was an open-label study performed at Kashani Hospital between April 2012 and June 2014. Patients with a <1 cm partial tearing of the bursal side of RC with no or little response to conservative management were included. PRP injection was done using ultrasonography guide via posterior subacromial approach. Demographic data were obtained in all patient before the study, and shoulder function was evaluated using Constant shoulder score (CSS) before and 3 months after PRP injection.
A total number of 17 patients were enrolled. The mean of CSS before and after intervention was 37.05 ± 11.03 and 61.76 ± 14.75, respectively ( < 0.001). There was no statistically significant correlation between the pain score before the study and the improvement in CSS ( = 0.45, = 0.03). Significant relation was observed between the individuals' age and improvement of CSS ( = 0.02, = -0.49). There was no significant difference in CSS improvement between genders ( = 0.23).
Single injection of PRP is effective to reduce pain and improve range of motion in patients with bursal side partial tearing of RC who failed to respond to conservative treatments.
肩袖(RC)的退行性改变和炎症是肩部疼痛的最重要原因。本研究的目的是确定富血小板血浆(PRP)对慢性RC肌腱病患者的有效性。
本研究是一项于2012年4月至2014年6月在卡沙尼医院进行的开放标签研究。纳入RC滑囊侧部分撕裂小于1 cm且对保守治疗无反应或反应轻微的患者。通过肩峰下后路采用超声引导进行PRP注射。在研究前获取所有患者的人口统计学数据,并在PRP注射前和注射后3个月使用Constant肩关节评分(CSS)评估肩关节功能。
共纳入17例患者。干预前后CSS的平均值分别为37.05±11.03和61.76±14.75(P<0.001)。研究前的疼痛评分与CSS的改善之间无统计学显著相关性(r = 0.45,P = 0.03)。观察到个体年龄与CSS改善之间存在显著相关性(P = 0.02,r = -0.49)。性别之间CSS改善无显著差异(P = 0.23)。
对于保守治疗无效的RC滑囊侧部分撕裂患者,单次注射PRP可有效减轻疼痛并改善活动范围。