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L-651,392: a novel, potent and selective 5-lipoxygenase inhibitor.

作者信息

Guindon Y, Girard Y, Maycock A, Ford-Hutchinson A W, Atkinson J G, Bélanger P C, Dallob A, DeSousa D, Dougherty H, Egan R

机构信息

Department of Medicinal Chemistry and Pharmacology, Merck Frosst Canada Inc., Pointe Claire-Dorval, Quebec.

出版信息

Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:554-7.

PMID:2821766
Abstract
摘要

相似文献

1
L-651,392: a novel, potent and selective 5-lipoxygenase inhibitor.L-651,392：一种新型、强效且具有选择性的5-脂氧合酶抑制剂。
Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:554-7.
2
Effects of a 5-lipoxygenase inhibitor (L-651,392) and leukotriene D4 antagonist (L-649,923) in two animal models of immediate hypersensitivity reactions.5-脂氧合酶抑制剂（L-651,392）和白三烯D4拮抗剂（L-649,923）在两种速发型超敏反应动物模型中的作用。
Adv Prostaglandin Thromboxane Leukot Res. 1987;17B:1007-11.
3
Wy-45,911: a novel leukotriene antagonist with lipoxygenase inhibitory activity.Wy-45,911：一种具有脂氧合酶抑制活性的新型白三烯拮抗剂。
Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:536-9.
4
5-Lipoxygenase inhibitors and allergic conjunctivitis reactions in the guinea-pig.5-脂氧合酶抑制剂与豚鼠过敏性结膜炎反应
Eur J Pharmacol. 1987 Nov 3;143(1):1-7. doi: 10.1016/0014-2999(87)90728-x.
5
Preferential inhibition of 5-lipoxygenase activity by manoalide.软海绵素对5-脂氧合酶活性的优先抑制作用。
Biochem Pharmacol. 1988 Aug 1;37(15):2899-905. doi: 10.1016/0006-2952(88)90274-2.
6
The regulation of 5-lipoxygenase activity in rat basophilic leukemia cells.
Adv Prostaglandin Thromboxane Leukot Res. 1990;20:28-34.
7
The use of leukotriene D4 receptor antagonists and 5-lipoxygenase inhibitors to define a role for leukotrienes in allergic reactions.
Adv Prostaglandin Thromboxane Leukot Res. 1989;19:507-10.
8
L-652,343: a novel dual 5-lipoxygenase/cyclooxygenase inhibitor.L-652,343：一种新型的5-脂氧合酶/环氧化酶双重抑制剂。
Adv Prostaglandin Thromboxane Leukot Res. 1986;16:63-6.
9
New lipoxygenase inhibitors isolated from Chinese plants. Development of new anti-allergic drugs.
Drugs Exp Clin Res. 1985;11(9):641-4.
10
Manipulations of arachidonic acid metabolism using a 5-lipoxygenase inhibitor in transfusion-induced immunosuppression.在输血诱导的免疫抑制中使用5-脂氧合酶抑制剂对花生四烯酸代谢进行调控。
Transplant Proc. 1988 Dec;20(6):1186-9.

引用本文的文献

1
Effect of manoalide on human 5-lipoxygenase activity.
Inflamm Res. 1996 May;45(5):218-23. doi: 10.1007/BF02259606.
2
L-651,392, a potent leukotriene inhibitor, controls inflammatory process in Escherichia coli pyelonephritis.L-651,392是一种强效白三烯抑制剂，可控制大肠杆菌性肾盂肾炎中的炎症过程。
Antimicrob Agents Chemother. 1994 Jul;38(7):1555-60. doi: 10.1128/AAC.38.7.1555.
3
The effect of non-steroidal anti-inflammatory drugs on the accumulation and release of interleukin-1-like activity by peritoneal macrophages from the mouse.非甾体抗炎药对小鼠腹腔巨噬细胞白细胞介素-1样活性积累和释放的影响。
Br J Pharmacol. 1994 Nov;113(3):809-14. doi: 10.1111/j.1476-5381.1994.tb17065.x.
4
Platelet activating factor and tracheobronchial respiratory glycoconjugate release in feline and human explants: involvement of the lipoxygenase pathway.
Agents Actions. 1990 Jun;30(3-4):329-37. doi: 10.1007/BF01966296.
5
Mesangial cell immune injury. Hemodynamic role of leukocyte- and platelet-derived eicosanoids.
J Clin Invest. 1992 Dec;90(6):2304-12. doi: 10.1172/JCI116118.