Hong Su Been, Lee Na Ra, Kim Seul Ki, Kim Hoon, Jee Byung Chul, Suh Chang Suk, Kim Seok Hyun, Choi Young Min
Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea.
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.
Obstet Gynecol Sci. 2017 Jan;60(1):63-68. doi: 10.5468/ogs.2017.60.1.63. Epub 2017 Jan 19.
To compare the fertilization (IVF) outcomes between women with diminished ovarian reserve (DOR) after endometrioma operation and women with DOR without ovarian surgery.
This retrospective case-control study included 124 women aged under 40 and had DOR (serum anti-Müllerian hormone level <1.1 ng/mL or antral follicle count ≤6). They participated in fresh first and/or second IVF cycles between March in 2010 and December in 2015. Basal characteristics and IVF outcomes were compared between 47 cycles (32 women) with surgery-induced DOR and 119 cycles (92 women) with DOR without ovarian surgery.
Basal characteristics were similar in both groups except that the median ages were lower in the surgery-induced DOR group compared to the DOR group without ovarian surgery. The data regarding the controlled ovarian stimulation and IVF cycle outcomes showed similar result in both groups. Also, clinical pregnancy and live birth rate were not different significantly between two groups.
In the same condition of DOR, clinical pregnancy and live birth rate were not different significantly between two groups regarding etiology of DOR.
比较子宫内膜异位囊肿手术后卵巢储备功能减退(DOR)的女性与未进行卵巢手术的DOR女性的体外受精(IVF)结局。
这项回顾性病例对照研究纳入了124名年龄在40岁以下且患有DOR(血清抗苗勒管激素水平<1.1 ng/mL或窦卵泡计数≤6)的女性。她们在2010年3月至2015年12月期间参与了首次和/或第二次新鲜IVF周期。比较了47个手术导致DOR的周期(32名女性)和119个未进行卵巢手术的DOR周期(92名女性)的基础特征和IVF结局。
两组的基础特征相似,只是手术导致DOR组的中位年龄低于未进行卵巢手术的DOR组。关于控制性卵巢刺激和IVF周期结局的数据在两组中显示出相似的结果。此外,两组之间的临床妊娠率和活产率没有显著差异。
在相同的DOR条件下,两组在DOR病因方面的临床妊娠率和活产率没有显著差异。