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超说明书用药与多药联用:降低风险

Off-Label Prescribing and Polypharmacy: Minimizing the Risks.

作者信息

Leahy Laura G

出版信息

J Psychosoc Nurs Ment Health Serv. 2017 Feb 1;55(2):17-22. doi: 10.3928/02793695-20170210-02.

DOI:10.3928/02793695-20170210-02
PMID:28218925
Abstract

Off-label prescribing and polypharmacy are commonplace in today's health care environment. Patients are treated with multiple medications obtained through multiple providers, and all too frequently, there is no collaboration amongst professionals. Nurses can address these issues by educating themselves and their patients regarding medication indications and uses, side effects, risks, and benefits. By exploring a patient's medication reconciliation, including over-the-counter agents, and identifying the U.S. Food and Drug Administration-approved indications, as well as potential off-label uses and overlapping side effects of the medications prescribed, nurses can facilitate collaboration among prescribers to reduce polypharmacy, minimize medication side effects, and alleviate drug-drug interactions, while improving patient outcomes and quality of life. [Journal of Psychosocial Nursing and Mental Health Services, 55(2), 17-22.].

摘要

在当今的医疗环境中,超说明书用药和多药联用现象很常见。患者会接受从多个医疗服务提供者处获取的多种药物治疗,而且专业人员之间常常缺乏协作。护士可以通过自我教育以及教育患者了解药物的适应症、用法、副作用、风险和益处来解决这些问题。通过探究患者的用药核对情况,包括非处方药,并确定美国食品药品监督管理局批准的适应症,以及所开药物的潜在超说明书用法和重叠的副作用,护士可以促进开方者之间的协作,以减少多药联用,将药物副作用降至最低,缓解药物相互作用,同时改善患者的治疗效果和生活质量。[《心理社会护理与精神卫生服务杂志》,第55卷第2期,第17 - 22页]

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